[HTML][HTML] CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach to fight cancers. This approach consists of …
promising immunotherapeutic approach to fight cancers. This approach consists of …
[HTML][HTML] CAR-NK cells: A promising cellular immunotherapy for cancer
Natural Killer (NK) cells and CD8+ cytotoxic T cells are two types of immune cells that can
kill target cells through similar cytotoxic mechanisms. With the remarkable success of …
kill target cells through similar cytotoxic mechanisms. With the remarkable success of …
[HTML][HTML] Natural killer cells: a promising immunotherapy for cancer
J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
[HTML][HTML] NK cell-based immune checkpoint inhibition
Immunotherapy, with an increasing number of therapeutic dimensions, is becoming an
important mode of treatment for cancer patients. The inhibition of immune checkpoints …
important mode of treatment for cancer patients. The inhibition of immune checkpoints …
Mild magnetic hyperthermia-activated innate immunity for liver cancer therapy
J Pan, Y Xu, Q Wu, P Hu, J Shi - Journal of the American Chemical …, 2021 - ACS Publications
Magnetic hyperthermia therapy (MHT) is noninvasive and features excellent tissue
penetration for deep-seated tumors, but unfortunately, it suffers the low therapeutic efficacy …
penetration for deep-seated tumors, but unfortunately, it suffers the low therapeutic efficacy …
[HTML][HTML] Aging of the immune system: focus on natural killer cells phenotype and functions
Aging is the greatest risk factor for nearly all major chronic diseases, including
cardiovascular diseases, cancer, Alzheimer's and other neurodegenerative diseases of …
cardiovascular diseases, cancer, Alzheimer's and other neurodegenerative diseases of …
[HTML][HTML] Tumor microenvironment of hepatocellular carcinoma: challenges and opportunities for new treatment options
Z Sas, E Cendrowicz, I Weinhäuser… - International Journal of …, 2022 - mdpi.com
The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
[HTML][HTML] Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer
Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are
important components of the tumor microenvironment, which have been reported to localize …
important components of the tumor microenvironment, which have been reported to localize …
[HTML][HTML] HBV-induced immune imbalance in the development of HCC
Y Chen, Z Tian - Frontiers in immunology, 2019 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is one of the high-risk factors for human HCC.
Despite the integration of virus DNA and the oncoprotein HBx, chronic necroinflammation …
Despite the integration of virus DNA and the oncoprotein HBx, chronic necroinflammation …
[PDF][PDF] Intrahepatic cholangiocarcinoma: continuing challenges and translational advances
Intrahepatic cholangiocarcinoma (iCCA) has over the last 10‐20 years become the focus of
increasing concern, largely due to its rising incidence and high mortality rates worldwide …
increasing concern, largely due to its rising incidence and high mortality rates worldwide …