Cells within cells: Rickettsiales and the obligate intracellular bacterial lifestyle

J Salje - Nature Reviews Microbiology, 2021 - nature.com
The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

[HTML][HTML] Unresolved problems related to scrub typhus: a seriously neglected life-threatening disease

DH Paris, TR Shelite, NP Day… - The American journal of …, 2013 - ncbi.nlm.nih.gov
Ecology and epidemiology. Scrub typhus is a life-threatening infectious disease that
presents as an acute undifferentiated febrile illness. Its agent, Orientia tsutsugamushi, is an …

Secretome of obligate intracellular Rickettsia

JJ Gillespie, SJ Kaur, MS Rahman… - FEMS Microbiology …, 2015 - academic.oup.com
The genus Rickettsia (Alphaproteobacteria, Rickettsiales, Rickettsiaceae) is comprised of
obligate intracellular parasites, with virulent species of interest both as causes of emerging …

Diagnosis of scrub typhus: recent advancements and challenges

D Kala, S Gupta, R Nagraik, V Verma, A Thakur… - 3 Biotech, 2020 - Springer
Scrub typhus is a mite-borne, acute febrile illness caused by the bacterium Orientia
tsutsugamushi. It is a re-emerging infectious disease of the tsutsugamushi triangle. Scrub …

[HTML][HTML] Phylogenetic classification and functional review of autotransporters

KR Clarke, L Hor, A Pilapitiya, J Luirink… - Frontiers in …, 2022 - frontiersin.org
Autotransporters are the core component of a molecular nano-machine that delivers cargo
proteins across the outer membrane of Gram-negative bacteria. Part of the type V secretion …

[HTML][HTML] Approaches to vaccines against Orientia tsutsugamushi

G Valbuena, DH Walker - Frontiers in cellular and infection …, 2013 - frontiersin.org
Scrub typhus is a severe mite-borne infection caused by Orientia tsutsugamushi, an
obligately intracellular bacterium closely related to Rickettsia. The disease explains a …

[HTML][HTML] Orientia tsutsugamushi: the dangerous yet neglected foe from the East

A Banerjee, S Kulkarni - International Journal of Medical Microbiology, 2021 - Elsevier
Orientia tsutsugamushi (OT), the causative agent of the vector-borne Scrub typhus zoonotic
disease in humans, is a unique microorganism that exists in the Asia-Pacific region since a …

Diversification of Orientia tsutsugamushi genotypes by intragenic recombination and their potential expansion in endemic areas

G Kim, NY Ha, CK Min, HI Kim, NTH Yen… - PLoS neglected …, 2017 - journals.plos.org
Background Scrub typhus is a mite-borne febrile disease caused by O. tsutsugamushi
infection. Recently, emergence of scrub typhus has attracted considerable attention in …

Moonlighting in Rickettsiales: expanding virulence landscape

AL Matos, P Curto, I Simões - Tropical medicine and infectious disease, 2022 - mdpi.com
The order Rickettsiales includes species that cause a range of human diseases such as
human granulocytic anaplasmosis (Anaplasma phagocytophilum), human monocytic …

Orientia tsutsugamushi Nucleomodulin Ank13 Exploits the RaDAR Nuclear Import Pathway To Modulate Host Cell Transcription

HE Adcox, AL Hatke, SE Andersen, S Gupta, NB Otto… - Mbio, 2021 - Am Soc Microbiol
Orientia tsutsugamushi is the etiologic agent of scrub typhus, the deadliest of all diseases
caused by obligate intracellular bacteria. Nucleomodulins, bacterial effectors that …