Epigenetic underpinnings of inflammation: Connecting the dots between pulmonary diseases, lung cancer and COVID-19

S Ahmad, S Manzoor, S Siddiqui, N Mariappan… - Seminars in cancer …, 2022 - Elsevier
Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …

Microbiota dysbiosis in select human cancers: evidence of association and causality

J Chen, JC Domingue, CL Sears - Seminars in immunology, 2017 - Elsevier
The human microbiota is a complex ecosystem of diverse microorganisms consisting of
bacteria, viruses, and fungi residing predominantly in epidermal and mucosal habitats …

[HTML][HTML] Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis

EA Marshall, KW Ng, SHY Kung, EM Conway… - Molecular cancer, 2016 - Springer
Lung cancer is a leading cause of cancer-related deaths worldwide. Lung cancer risk
factors, including smoking and exposure to environmental carcinogens, have been linked to …

Research progress and value of albumin-related inflammatory markers in the prognosis of non-small cell lung cancer: A review of clinical evidence

C Zhang, M Gao, X Jiang, X Pan, X Zhang, Y Li… - Annals of …, 2023 - Taylor & Francis
Inflammatory markers have a wide range of predictive values in the prognosis of non-small
lung cancer (NSCLC). Poor nutritional status usually means a poor prognosis in patients …

Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?

K Jahankhani, F Ahangari, IM Adcock, E Mortaz - Biochimie, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown diverse life-
threatening effects, most of which are considered short-term. In addition to its short-term …

A review of pulmonary toxicity of electronic cigarettes in the context of smoking: a focus on inflammation

PG Shields, M Berman, TM Brasky… - … Biomarkers & Prevention, 2017 - AACR
The use of electronic cigarettes (e-cigs) is increasing rapidly, but their effects on lung toxicity
are largely unknown. Smoking is a well-established cause of lung cancer and respiratory …

Association between chest CT–defined emphysema and lung cancer: a systematic review and meta-analysis

X Yang, HJ Wisselink, R Vliegenthart, MA Heuvelmans… - Radiology, 2022 - pubs.rsna.org
Background Given the different methods of assessing emphysema, controversy exists as to
whether it is associated with lung cancer. Purpose To perform a systematic review and meta …

Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6-mediated COX-2/PGE2/β-catenin signalling pathway

D Che, S Zhang, Z Jing, L Shang, S Jin, F Liu… - Molecular …, 2017 - Elsevier
Infiltration of macrophages plays a critical role in the connection between inflammation and
cancer invasion; however, the molecular mechanism that enables this crosstalk remains …

Overall and central obesity and risk of lung cancer: a pooled analysis

D Yu, W Zheng, M Johansson, Q Lan… - JNCI: Journal of the …, 2018 - academic.oup.com
Background The obesity–lung cancer association remains controversial. Concerns over
confounding by smoking and reverse causation persist. The influence of obesity type and …

[HTML][HTML] The role of the ECM in lung cancer dormancy and outgrowth

AL Parker, TR Cox - Frontiers in oncology, 2020 - frontiersin.org
The dissemination of tumor cells to local and distant sites presents a significant challenge in
the clinical management of many solid tumors. These cells may remain dormant for months …