Juvenile dermatomyositis (JDM) is a rare heterogeneous immune-medicated condition with
characteristic skin rashes, muscle weakness, vasculopathy, and other organ involvement …

Abstract Purpose of Review Although rare, idiopathic inflammatory myopathies (IIM)
comprise a heterogeneous group of autoimmune conditions in adults and children …

Background Dermatomyositis (DM) manifests as an autoimmune and inflammatory
condition, clinically characterized by subacute progressive proximal muscle weakness …

Tissue-resident memory T cells (TRM) are suspected drivers of chronic inflammation, but
their induction remains unclear. Since endothelial cells (EC) are obligate interaction …

Aim Endothelial dysfunction represents a key feature of the pathological process underlying
micro and macro-vascular damage in Systemic Sclerosis (SSc). This study aims to improve …

Inflammatory coagulopathy is resulted from endothelial dysfunction and platelet
hyperactivation in inflammatory diseases. In this study, the effects of baicalin, an active …

Objectives To study the phenotype of macrophage infiltrates and their role in angiogenesis
in different idiopathic inflammatory myopathies (IIMs). Methods The density and distribution …

Background Subtypes of pulmonary arterial hypertension (PAH) differ in both fundamental
disease features and clinical outcomes. Angiogenesis and inflammation represent disease …

Spinal muscular atrophy (SMA) is a progressive motor neuron disease with onset during
infancy or early childhood. Recent therapeutic advances targeting the genetic defect that …

Objectives Dermatomyositis (DM) and anti-synthetase syndrome (ASS) are autoimmune
diseases with multisystem involvement. Despite sharing some clinical and myopathological …