Chagas disease in the United States: a public health approach

C Bern, LA Messenger, JD Whitman… - Clinical microbiology …, 2019 - Am Soc Microbiol
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

Current drug therapy and pharmaceutical challenges for Chagas disease

J Bermudez, C Davies, A Simonazzi, JP Real, S Palma - Acta tropica, 2016 - Elsevier
One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

Unraveling Chagas disease transmission through the oral route: Gateways to Trypanosoma cruzi infection and target tissues

D Silva-dos-Santos… - PLoS neglected …, 2017 - journals.plos.org
Oral transmission of Trypanosoma cruzi, the causative agent of Chagas disease, is the most
important route of infection in Brazilian Amazon and Venezuela. Other South American …

Prognosis of chronic Chagas heart disease and other pending clinical challenges

RM Torres, D Correia, MCP Nunes… - Memórias do Instituto …, 2022 - SciELO Brasil
In this chapter, the main prognostic markers of Chagas heart disease are addressed, with an
emphasis on the most recent findings and questions, establishing the basis for a broad …

Central nervous system commitment in Chagas disease

Y Useche, AR Pérez, J De Meis, A Bonomo… - Frontiers in …, 2022 - frontiersin.org
The involvement of the central nervous system (CNS) during human acute and chronic
Chagas disease (CD) has been largely reported. Meningoencephalitis is a frequent finding …

Understanding the oral transmission of Trypanosoma cruzi as a veterinary and medical foodborne zoonosis

N Velásquez-Ortiz, JD Ramírez - Research in veterinary science, 2020 - Elsevier
Chagas disease is a neglected tropical disease transmitted by the protozoan Trypanosoma
cruzi that lately has been highlighted because several outbreaks attributed to oral …

Orally-transmitted Chagas disease

MT Filigheddu, M Górgolas, JM Ramos - Medicina Clínica (English Edition), 2017 - Elsevier
Chagas disease is a zoonosis caused by protozoan parasite Trypanosoma cruzi, which is
most frequently associated with a vectorial transmission. However, in recent years we have …

Enfermedad de Chagas de transmisión oral

MT Filigheddu, M Górgolas, JM Ramos - Medicina clínica, 2017 - Elsevier
La enfermedad de Chagas es una zoonosis causada por el parásito protozoario
Trypanosoma cruzi, transmitido con mayor frecuencia por vía vectorial. En los últimos años …

Imaging the development of chronic Chagas disease after oral transmission

MD Lewis, AF Francisco, S Jayawardhana… - Scientific reports, 2018 - nature.com
Chagas disease is a zoonosis caused by the protozoan parasite Trypanosoma cruzi.
Transmission cycles are maintained by haematophagous triatomine bug vectors that carry …

Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology

K Hoffman, Z Liu, E Hossain, ME Bottazzi… - ACS infectious …, 2021 - ACS Publications
Chronic Chagasic cardiomyopathy (CCC) is a Neglected Tropical Disease caused by the
parasite Trypanosoma cruzi. The pathognomonic findings in symptomatic CCC patients and …