The onset of clinical assisted reproduction, a quarter of a century ago, required the isolation
of motile spermatozoa. As the indication of assisted reproduction shifted from mere …

The blood‐testis barrier (BTB) in mammals, such as rats, is composed of the tight junction
(TJ), the basal ectoplasmic specialization (basal ES), the basal tubulobulbar complex (basal …

In this article, we focus on the fundamental role of vitamin C transporters for the normal
delivery of vitamin C to germ cells in the adluminal compartment of seminiferous tubules. We …

Induction of meiotic and post-meiotic alterations of male germ cells in vitro has been the
target of several research efforts since 1960. However, to date, the establishment of an ideal …

Kinins are peptide hormones that transmit their biological effects via G protein‐coupled
receptors. They are generated by kallikrein‐mediated proteolysis of their precursors, the …

Angiotensin I‐converting enzyme (ACE; CD143, Kininase II, EC 3.4. 15.1) is known to be
crucial for male fertility in animal models. We therefore studied its testicular (tACE) and …

The Angiotensin-converting enzyme (Ance) gene of Drosophila melanogaster is a
homologue of mammalian angiotensin-converting enzyme (ACE), a peptidyl dipeptidase …

The angiotensin I‐converting enzyme (ACE, kininase II, CD143) shows a broad specificity
for various oligopeptides. Besides the well‐known conversion of angiotensin I to II, ACE …

RT–PCR and Western blots were used to detect bradykinin B2 receptors in testis and
isolated peritubular cells of pre‐pubertal rats. RT–PCR demonstrated expression of a single …

To investigate the possible role of the local tissue kallikrein-kinin system in
spermatogenesis, we analyzed gene expression and cellular distribution of the bradykinin …