Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions
Antimicrobial resistance (AMR) is a global health challenge that threatens humans, animals
and the environment. Evidence is emerging for a role of healthcare infrastructure …
and the environment. Evidence is emerging for a role of healthcare infrastructure …
Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1–4: A …
P Arkell, D Mairiang, A Songjaeng… - PLOS Global Public …, 2023 - journals.plos.org
Dengue is a mosquito-borne disease caused by dengue virus (DENV) serotypes 1–4 which
affects 100–400 million adults and children each year. Reverse-transcriptase (RT) …
affects 100–400 million adults and children each year. Reverse-transcriptase (RT) …
Deep learning enhanced multiplex detection of viable foodborne pathogens in digital microfluidic chip
H Quan, S Wang, X Xi, Y Zhang, Y Ding, Y Li… - Biosensors and …, 2024 - Elsevier
Culture plating is worldwide accepted as the gold standard for quantifying viable foodborne
pathogens. However, it is time-consuming (1–2 days) and requires specialized laboratory …
pathogens. However, it is time-consuming (1–2 days) and requires specialized laboratory …
Rapid, Portable, and Electricity-free Sample Extraction Method for Enhanced Molecular Diagnostics in Resource-Limited Settings
I Pennisi, ML Cavuto, L Miglietta… - Analytical …, 2024 - ACS Publications
The COVID-19 pandemic has highlighted the need for rapid and reliable diagnostics that are
accessible in resource-limited settings. To address this pressing issue, we have developed …
accessible in resource-limited settings. To address this pressing issue, we have developed …
A computational framework to improve cross-platform implementation of transcriptomics signatures
The emergence of next-generation sequencing technologies and computational advances
have expanded our understanding of gene expression regulation (ie, the transcriptome) …
have expanded our understanding of gene expression regulation (ie, the transcriptome) …
Deep domain adaptation enhances amplification curve analysis for single-channel multiplexing in real-time PCR
Data-driven approaches for molecular diagnostics are emerging as an alternative to perform
an accurate and inexpensive multi-pathogen detection. A novel technique called …
an accurate and inexpensive multi-pathogen detection. A novel technique called …
Multiplex detection of bacterial pathogens by PCR/SERS assay
Bacterial infections are a leading cause of death globally. The detection of DNA sequences
correlated to the causative pathogen has become a vital tool in medical diagnostics. In …
correlated to the causative pathogen has become a vital tool in medical diagnostics. In …
Molecular diagnostics: past, present, and future
Abstract “The major credit I think Jim and I deserve… is for selecting the right problem and
sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that …
sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that …
Exploring the feasibility of utilizing universal primers in detecting mucormycosis pathogens: An in-silico analysis
S Gunathilaka, S Bandara, I Senevirathna… - … and Infectious Disease, 2024 - Elsevier
This study aimed to design and evaluate a universal primer for Polymerase Chain Reaction
(PCR)-based detection of mucormycosis-causing fungi by targeting their Internal …
(PCR)-based detection of mucormycosis-causing fungi by targeting their Internal …
Isomeric differentiation of bile acids using three‐dimensional MS2 spectrum
X Niu, Y Zhou, W Zhao, X Li, L Ren, P Tu… - Journal of the …, 2024 - Wiley Online Library
Bile acids (BAs) currently occupy the research hotspot because of their unreplaceable
physiological functions as well as their unique abilities to reflect the physiopathological …
physiological functions as well as their unique abilities to reflect the physiopathological …