Biological and pharmacological effects of gamma-oryzanol: An updated review of the molecular mechanisms

E Ramazani, M Akaberi, SA Emami… - Current …, 2021 - ingentaconnect.com
Background: Gamma-oryzanol (γ-oryzanol) is one of the rice bran oil (RBO) compounds,
known as a principal food source throughout the world. In recent numerous experimental …

[HTML][HTML] Adiponectin in renal fibrosis

H Jing, S Tang, S Lin, M Liao, H Chen, Y Fan… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Renal fibrosis is an inevitable consequence of parenchymal scarring and is the common
final pathway that mediates almost all progressive renal diseases. Adiponectin, a hormone …

Antioxidant and anti-inflammatory properties of gamma-oryzanol attenuates insulin resistance by increasing GLUT-4 expression in skeletal muscle of obese animals

L Mattei, FV Francisqueti-Ferron, JL Garcia… - Molecular and cellular …, 2021 - Elsevier
Background Skeletal muscle is the most important organ for whole-body glucose
homeostasis. However, it has been suggested that obesity-related inflammation could be …

Bergamot leaf extract treats cardiorenal metabolic syndrome and associated pathophysiological factors in rats fed with a high sugar fat diet

JS Siqueira, TA Vieira, ET Nakandakare-Maia… - Molecular and Cellular …, 2022 - Elsevier
Abstract Bergamot citrus (Citrus bergamia Risso et Poiteau), have been used as a strategy
to prevent or treat comorbidities associated with metabolic syndrome parameters, such as …

CD36‐mediated lipid accumulation and activation of NLRP3 inflammasome lead to podocyte injury in obesity‐related glomerulopathy

J Zhao, H Rui, M Yang, L Sun, H Dong… - Mediators of …, 2019 - Wiley Online Library
Podocyte injury critically contributes to the pathogenesis of obesity‐related glomerulopathy
(ORG). Recently, lipid accumulation and inflammatory responses have been found to be …

[HTML][HTML] Comparative study of gavage and intraperitoneal administration of gamma-oryzanol in alleviation/attenuation in a rat animal model of renal ischemia …

Y Bagheri, A Barati, S Nouraei, NJ Namini… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): Ischemia/reperfusion (I/R) is the leading cause of acute kidney injury. This
study aimed to elucidate the reno-protective effect of gamma-oryzanol (GO) by comparing …

Gamma-oryzanol as a potential modulator of oxidative stress and inflammation via PPAR-y in adipose tissue: a hypothetical therapeutic for cytokine storm in COVID …

FV Francisqueti-Ferron, JL Garcia, AJT Ferron… - Molecular and Cellular …, 2021 - Elsevier
The literature has reported a higher prevalence of negative clinical outcomes due to
Coronavirus disease 19 (COVID-19) in obese individuals. This can be explained by the …

Treatment with bergamot (Citrus bergamia) leaves extract attenuates leptin resistance in obese rats

ET Nakandakare-Maia, JS Siqueira, AJT Ferron… - Molecular and Cellular …, 2023 - Elsevier
Low-grade chronic inflammation in obesity is associated with leptin resistance. In order to
alleviate this pathological condition, bioactive compounds capable of attenuating oxidative …

Advances in understanding the role of adiponectin in renal fibrosis

D Zhao, X Zhu, L Jiang, X Huang, Y Zhang, X Wei… - …, 2021 - Wiley Online Library
Renal fibrosis is characterized by the proliferation of renal intrinsic cells, activation of renal
interstitial fibroblasts and deposition of extracellular matrix (ECM), processes that lead to the …

[HTML][HTML] Effect of Bergamot Leaves (Citrus bergamia) in the Crosstalk between Adipose Tissue and Liver of Diet-Induced Obese Rats

JS Siqueira, ET Nakandakare-Maia, TA Vieira… - Livers, 2023 - mdpi.com
The excessive consumption of diets rich in sugar and fat is associated with metabolic
manifestations involving adipose tissue and the liver. Bergamot, due to its antioxidant and …