Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …

Over the past decade, colorectal cancer has reported a higher incidence in younger adults
and a lower mortality rate. Recently, the influence of the intestinal flora in the initiation …

Abstract Introduction Bisphenol A (BPA) is a widespread environmental pollutant which has
serious toxic effects on organisms. One of the crucial trace elements is selenium (Se), whose …

Background Doxorubicin (DOX) is a powerful anti-tumor anthracycline drug. However, its
clinical use is limited due to the side effect of cardiotoxicity. Tanshinone I (Tan I) is one of the …

Background Silymarin, a blend of flavonolignans isolated from plant Silybum marianum L.,
has long been used as an herbal medicine. Biogenic routes especially the plant-based …

Cancer has always been a worldwide problem, and the application of radiotherapy has
greatly improved the survival rate of cancer patients. Radiotherapy can modulate multiple …

Ovarian cancer is mostly diagnosed at an advanced stage due to the absence of effective
screening methods and specific symptoms. Repeated chemotherapy resistance and …

Nanoplastics (NPs), as emerging pollutants, have attracted global attention. Nevertheless,
the adverse effects of NPs on female reproductive health, especially unexplained …

Non-alcoholic fatty liver disease (NAFLD) is the most common among lipid metabolism
disorders. Autophagy plays an important role in lipid metabolism in NAFLD. Pueraria …

Intervertebral disc degeneration (IVDD) is the main cause of cervical and lumbar
spondylosis. Over the past few years, the relevance between cellular senescence and IVDD …