Chemistry is progressively unraveling the processes that underlie the evolution of matter
towards states of higher complexity and the generation of novel features along the way by …

Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …

Photothermal therapy (PTT) is recognized as a promising approach for cancer theranostics
via the nonradiative conversion of light into heat energy. PTT treatment is able to reduce the …

Despite encouraging results from preliminary studies of anticancer therapies, the lack of
tumor specificity remains an important issue in the modern pharmaceutical industry. New …

In the past two decades, extensive efforts have been made to develop agents targeting
prostate-specific membrane antigen (PSMA) for prostate cancer imaging and therapy. To …

In this review article we discuss some of the key aspects concerning the development of a
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …

We describe the development of OncoFAP, an ultra-high-affinity ligand of fibroblast
activation protein (FAP) for targeting applications with pan-tumoral potential. OncoFAP binds …

Antibody–drug conjugates are a very promising class of new anticancer agents, but the use
of small‐molecule ligands for the targeted delivery of cytotoxic drugs into solid tumors is less …

Antibody–drug conjugates (ADCs) consist of cytotoxic drugs covalently linked to monoclonal
antibodies directed to antigens differentially overexpressed in tumor cells. These loaded …

Nanomedicine, the application of nanotechnology to medicine, is being increasingly used to
improve and exploit the advantages of efficient drug delivery. Different nanodevices have …