Immunization with the adjuvant MF59 induces macrophage trafficking and apoptosis

M Dupuis, K Denis‐Mize, A LaBarbara… - European journal of …, 2001 - Wiley Online Library
The mechanisms associated with the immunostimulatory activity of vaccine adjuvants are
still poorly understood. We have undertaken a study to determine whether antigen …

Cross-protection by MF59™-adjuvanted influenza vaccine: Neutralizing and haemagglutination-inhibiting antibody activity against A (H3N2) drifted influenza viruses

F Ansaldi, S Bacilieri, P Durando, L Sticchi, L Valle… - Vaccine, 2008 - Elsevier
Adjuvants enhance antibody response against vaccination. We compared the ability of
MF59™-adjuvanted and non-adjuvanted subunit influenza vaccines, containing …

Challenges in adult vaccination

E de Gomensoro, G Del Giudice, TM Doherty - Annals of medicine, 2018 - Taylor & Francis
Life-long primary prevention interventions beginning and continuing throughout an
individual's lifetime are increasingly seen as key to meeting the global healthcare …

MF59®-adjuvanted influenza vaccine (FLUAD®) in children: Safety and immunogenicity following a second year seasonal vaccination

T Vesikari, N Groth, A Karvonen, A Borkowski… - Vaccine, 2009 - Elsevier
After priming with two intramuscular doses of MF59®-adjuvanted (Sub/MF59) or split
influenza vaccines during the 2006/07 season, 89 healthy children received a third booster …

Adjuvanted versus nonadjuvanted influenza vaccines and risk of hospitalizations for pneumonia and cerebro/cardiovascular events in the elderly

F Lapi, E Marconi, M Simonetti, V Baldo… - Expert review of …, 2019 - Taylor & Francis
Background: The higher effectiveness of MF59®-adjuvanted trivalent influenza vaccine
(MF59-TIV) vs. nonadjuvanted TIV in preventing influenza-related hospitalizations was …

Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators

P Nordly, HB Madsen, HM Nielsen… - Expert opinion on drug …, 2009 - Taylor & Francis
Vaccines seek to adopt pathogen-like characteristics but not true pathogen characteristics to
activate the immune system without causing life-threatening disease. Vaccine formulations …

Strategies to alleviate original antigenic sin responses to influenza viruses

JH Kim, WG Davis, S Sambhara… - Proceedings of the …, 2012 - National Acad Sciences
Original antigenic sin is a phenomenon wherein sequential exposure to closely related
influenza virus variants reduces antibody (Ab) response to novel antigenic determinants in …

Iron nanoparticles as novel vaccine adjuvants

M Behzadi, B Vakili, A Ebrahiminezhad… - European journal of …, 2021 - Elsevier
The poor immunogenicity of peptide vaccines compared to conventional ones re usually
improved by applying different adjuvants. As chemical or biological substances, adjuvants …

Influenza immunization during pregnancy: Benefits for mother and infant

IG Sakala, Y Honda-Okubo, J Fung… - Human vaccines & …, 2016 - Taylor & Francis
The serious consequences of influenza infection during pregnancy have been recognized
for almost a century. In this article, we reviewed the evidence on the immunogenicity, safety …

[HTML][HTML] Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS

D Nehar-Belaid, M Sokolowski, S Ravichandran… - Seminars in …, 2023 - Elsevier
Vaccines are among the greatest inventions in medicine, leading to the elimination or
control of numerous diseases, including smallpox, polio, measles, rubella, and, most …