Vaccines represent the most efficient tool for preventing diseases caused by infectious
pathogens. During the last century significant progress has been made in vaccine …

Traditional influenza vaccines generate strain-specific antibodies which cannot provide
protection against divergent influenza virus strains. Further, due to frequent antigenic shifts …

Exposure to the hydrocarbon oil pristane induces lupus specific autoantibodies in non-
autoimmune mice. We investigated whether the capacity to induce lupus-like autoimmunity …

Background Although seasonal influenza vaccine is effective in the elderly, immune
responses to vaccination are lower in the elderly than in younger adults. Strategies to …

A randomised, open study was carried out among an elderly population in order to compare
the reactogenicity and immunogenicity of an inactivated, split virion influenza vaccine …

Nanotechnology uses the unique properties of nanostructures with a size of 1 to 200
nanometers. Different nanoparticles have shown great promise for the production of new …

Vaccination has a great impact on the prevention and control of infectious diseases.
However, there are still many infectious diseases for which an effective vaccine is missing …

It is thought that the development of vaccines for the treatment of infectious diseases and
cancer is likely to be achieved in the coming decades. This is partially due to a better …

The MF59 adjuvant has been included in a licensed influenza vaccine for a decade. Hence,
we have a significant amount of clinical data to establish its potency and safety. We can now …

We investigated trends in influenza-related mortality among the elderly population in Italy
associated with increased vaccination coverage. Using Italian vital statistics data, we studied …