Mode of action of adjuvants: implications for vaccine safety and design

B Mastelic, S Ahmed, WM Egan, G Del Giudice… - Biologicals, 2010 - Elsevier
For decades, the search for new vaccine adjuvants has been largely empirical. A series of
new adjuvants and related formulations are now emerging that are acting through identified …

Immunogenicity of intramuscular MF59-adjuvanted and intradermal administered influenza enhanced vaccines in subjects aged over 60: a literature review

B Camilloni, M Basileo, S Valente… - Human vaccines & …, 2015 - Taylor & Francis
Because of the age-related immune system decline, 2 potentiated influenza vaccines were
specifically licensed for the elderly: Fluad®, an MF59-adjuvanted vaccine administered …

H1N1 vaccines in a large observational cohort of patients with inflammatory bowel disease treated with immunomodulators and biological therapy

JF Rahier, P Papay, J Salleron, S Sebastian, M Marzo… - Gut, 2011 - gut.bmj.com
Background Safety data are lacking on influenza vaccination in general and on A (H1N1) v
vaccination in particular in patients with inflammatory bowel disease (IBD) receiving …

Seasonal influenza immunisation: strategies for older adults

W Schaffner, P van Buynder, S McNeil… - … journal of clinical …, 2018 - Wiley Online Library
Adults over the age of 60‐65 years suffer disproportionally from seasonal influenza,
experiencing high rates of complications, exacerbation of underlying medical comorbidities …

Bacterial ghosts as adjuvant particles

EM Riedmann, JM Kyd, AW Cripps… - Expert review of …, 2007 - Taylor & Francis
The development of more advanced and effective vaccines is of great interest in modern
medicine. These new-generation vaccines, based on recombinant proteins or DNA, are …

Evaluation of properties of chitosan as an adjuvant for inactivated influenza vaccines administered parenterally

Y Ghendon, S Markushin, Y Vasiliev… - Journal of Medical …, 2009 - Wiley Online Library
Studies on mice showed that chitosan as an adjuvant for H5 inactivated influenza vaccines
administered intramuscularly enhances significantly antibody titers and protective efficiency …

Adjuvants and alternative routes of administration towards the development of the ideal influenza vaccine

P Durando, R Iudici, C Alicino, M Alberti… - Human …, 2011 - Taylor & Francis
Vaccination is universally considered as the principal measure for the control of influenza,
which represents a significant burden worldwide, both from a health-care and a socio …

Classification of vaccines

RS Kallerup, C Foged - Subunit vaccine delivery, 2014 - Springer
Vaccination has contributed significantly to improving public health by reducing the mortality
caused by a number of infectious diseases. Thanks to extensive childhood vaccination …

Comparison of the safety, tolerability, and immunogenicity of a MF59-adjuvanted influenza vaccine and a non-adjuvanted influenza vaccine in non-elderly adults

S Frey, G Poland, S Percell, A Podda - Vaccine, 2003 - Elsevier
The adjuvanted influenza vaccine FLUAD™ is composed of subunit influenza antigens
combined with the MF59-adjuvant emulsion. The vaccine was developed primarily for use in …

Evidence of increased clinical protection of an MF59-adjuvant influenza vaccine compared to a non-adjuvant vaccine among elderly residents of long-term care …

A Iob, G Brianti, E Zamparo, T Gallo - Epidemiology & Infection, 2005 - cambridge.org
We evaluated whether the increased immunogenicity provided by an MF59-adjuvant
influenza vaccine translates into increased protection among the elderly. Residents of 25 …