The nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly prescribed by medical
practitioners in many clinical conditions for the symptomatic treatment of pain and fever. Due …

Gastrointestinal (GI) side-effects of chemotherapy are a debilitating and often overlooked
clinical hurdle in cancer management. Chemotherapy-induced constipation (CIC) and …

It is well known that many tumours are potentially immunogenic, as corroborated by the
presence of tumour-specific immune responses in vivo. Nonetheless, spontaneous …

Surgical excision is the mainstay of treatment for potentially curable solid tumours.
Metastatic disease is the most important cause of cancer-related death in these patients. The …

Chronic inflammation plays a multifaceted role in carcinogenesis. Mounting evidence from
preclinical and clinical studies suggests that persistent inflammation functions as a driving …

Increasing evidence from animal and in vitro studies indicates that n− 3 fatty acids,
especially the long-chain polyunsaturated fatty acids eicosapentaenoic acid and …

Myeloid suppressor cells (MSCs) producing high levels of arginase I block T cell function by
depleting l-arginine in cancer, chronic infections, and trauma patients. In cancer, MSCs …

Cyclooxygenase (COX), a key enzyme in the prostanoid biosynthetic pathway, has received
considerable attention due to its role in human cancers. Observational and randomized …

Two major challenges facing cancer immunotherapy are the relatively low therapeutic
efficacy and the potential side effects. New drug delivery system and efficient drug …

Drinking green tea is associated with decreased frequency of cancer development. This
review outlines the wide range of mechanisms by which epigallocatechin gallate (ECGC) …