A new era of nanomedicines that involve nucleic acids/gene therapy has been opened after
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …

Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …

The combination of multiple therapeutic modalities has attracted increasing attention as it
can achieve better therapeutic effects through different treatment mechanisms. However …

Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Nanosystems for targeted delivery of cargos to mitochondria for cancer …

The variable clinical and biochemical manifestations of primary mitochondrial diseases
(PMDs), and the complexity of mitochondrial genetics, have proven to be a substantial …

Mitochondrial diseases (MDs) may result from mutations affecting nuclear or mitochondrial
genes, encoding mitochondrial proteins, or non-protein-coding mitochondrial RNA. Despite …

Biodegradable nanostructures displaying aggregation‐induced emission (AIE) are desirable
from a biomedical point of view, due to the advantageous features of loading capacity …

Mitochondria play an essential role in cellular metabolism and generate energy in cells. To
support these functions, several proteins are encoded in the mitochondrial DNA (mtDNA) …

Dilated cardiomyopathy (DCM) is a leading cause of heart failure and the most common
indication for heart transplantation. Currently, there is still an unmet clinical need in effective …

In order to artificially regulate cell behaviors, intracellular polymerization as an emerging
chemical technique has attracted much attention. Yet, it is still a challenge to achieve …