Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Inflammation and sarcopenia: a systematic review and meta-analysis

G Bano, C Trevisan, S Carraro, M Solmi, C Luchini… - Maturitas, 2017 - Elsevier
Inflammatory cytokines have been shown to prompt muscle wasting, ultimately stimulating
protein catabolism and suppressing muscle synthesis. However, the possible association …

Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases

A Bleve, F Motta, B Durante, C Pandolfo… - Clinical reviews in …, 2022 - Springer
The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

Sarcopenia in older adults

JD Walston - Current opinion in rheumatology, 2012 - journals.lww.com
Efforts to develop a consensus definition are ongoing and will greatly facilitate the
development and testing of novel interventions for sarcopenia. Although pharmaceutical …

Respiratory sarcopenia and sarcopenic respiratory disability: concepts, diagnosis, and treatment

A Nagano, H Wakabayashi, K Maeda, Y Kokura… - The journal of nutrition …, 2021 - Springer
The condition of muscle fiber atrophy and weakness that occurs in respiratory muscles along
with systemic skeletal muscle with age is known as respiratory sarcopenia. The Japanese …

Sarcopenia and inflammatory bowel disease: a systematic review

E Ryan, D McNicholas, B Creavin… - Inflammatory Bowel …, 2019 - academic.oup.com
Background Sarcopenia is associated with increased morbidity and mortality in oncologic
and transplant surgery. It has a high incidence in chronic inflammatory states including …

Sarcopenia and frailty in older patients with diabetes mellitus

H Umegaki - Geriatrics & gerontology international, 2016 - Wiley Online Library
Sarcopenia is defined as age‐associated loss of muscle mass and function, and is
frequently accompanied by diabetes mellitus (DM) in older adults. Some of the mechanisms …

[HTML][HTML] Inflammation and age-associated skeletal muscle deterioration (sarcopaenia)

J Wang, KS Leung, SKH Chow, WH Cheung - Journal of orthopaedic …, 2017 - Elsevier
Ageing is accompanied by chronic inflammatory responses due to elevated circulatory
inflammatory cytokine production. Several inflammatory cytokines have been shown to be …

Cellular senescence in sarcopenia: possible mechanisms and therapeutic potential

Y He, W Xie, H Li, H Jin, Y Zhang, Y Li - Frontiers in Cell and …, 2022 - frontiersin.org
Aging promotes most degenerative pathologies in mammals, which are characterized by
progressive decline of function at molecular, cellular, tissue, and organismal levels and …

Low muscle mass and sarcopenia: common and predictive of osteopenia in inflammatory bowel disease

RV Bryant, S Ooi, CG Schultz, C Goess… - Alimentary …, 2015 - Wiley Online Library
Background Body composition is poorly studied in inflammatory bowel disease (IBD).
Sarcopenia describes a loss of muscle mass and strength. Aim To assess the prevalence of …