Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

Neuroinflammation and neurodegeneration often result from the aberrant deposition of
aggregated host proteins, including amyloid‐β, α‐synuclein, and prions, that can activate …

As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Inflammation is currently considered a prime target for the development of new stroke
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …

The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …

Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa.
Sleep-inducing inflammatory molecules are activated by increased waking activity and …