Advances in areas that include genomics, systems biology, protein structure determination
and artificial intelligence provide new opportunities for target-based antibacterial drug …

Antibiotic resistance (ABR) is a dire global health crisis, undermining the efficacy of
antibiotics and ranking among the top ten public health threats according to the World …

To address the threat of bacterial infection in the following post-antibiotic era, developing
effective antibacterial approaches is of utmost urgency. Theranostic medicine integrating …

Antimicrobial resistance (AMR) has become more of a concern in recent decades,
particularly in infections associated with global public health threats. The development of …

Introduction: Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp., commonly
referred to as TriTryps, are a group of protozoan parasites that cause important human …

Phenotypic screening is a powerful technique that allowed the discovery of antimicrobials to
fight infectious diseases considered deadly less than a century ago. In high throughput …

Listeria monocytogenes (Lm) is a gram-positive bacillus responsible for listeriosis in
humans. Listeriosis has become a major foodborne illness in recent years. This illness is …

In this study, we investigated the in vitro activity and resistance mechanisms of the new
generation tetracycline agents, namely eravacycline, omadacycline, and tigecycline, against …

Bacterial P450 cytochromes (BacCYPs) are versatile heme-containing proteins responsible
for oxidation reactions on a wide range of substrates, contributing to the production of …

Nanomaterials based therapeutics transform the ways of disease prevention, diagnosis and
treatment with increasing sophistications in nanotechnology at a breakneck pace, but very …