Multiple sclerosis (MS) is a complex neurodegenerative disease affecting the central
nervous system (CNS). The onset of MS has been typically observed in individuals aged …

Multiple sclerosis (MS) is a common, disabling, putatively autoimmune neurological disease
with worldwide distribution. It typically begins as a relapsing disorder that later evolves to a …

In multiple sclerosis (MS), iron accumulates inside activated microglia/macrophages at
edges of some chronic demyelinated lesions, forming rims. In susceptibility-based magnetic …

Autoimmunity plays a significant role in the pathogenesis of demyelination. Multiple
sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD) and myelin …

The progressive patterns of neurological disability in multiple sclerosis (MS) and
neuromyelitis optica spectrum disorders (NMOSD) and the significance of clinical relapses …

Neurodegenerative diseases are relentlessly progressive, severely impacting affected
patients, families and society as a whole. Increased life expectancy has made these …

Multiple sclerosis (MS) is a chronic central nervous system disease that is associated with
progressive loss of myelin and subsequent axonal degeneration. Cholesterol is an essential …

Identifying effective therapies for the treatment of progressive forms of multiple sclerosis
(MS) is a highly relevant priority and one of the greatest challenges for the global MS …

Fatigue is one of the most disabling symptoms of multiple sclerosis (MS); it influences
patients' quality of life. The etiology of fatigue is complex, and its pathogenesis is still unclear …

Progressive multiple sclerosis (MS) is characterized clinically by the accumulation of
neurological disability without unequivocal recovery. Understanding the mechanisms that …