[HTML][HTML] Marine natural products

JW Blunt, AR Carroll, BR Copp, RA Davis… - Natural product …, 2018 - pubs.rsc.org
Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235–294 This review covers the
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …

[HTML][HTML] Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review

CL Wainwright, MM Teixeira, DL Adelson… - Pharmacological …, 2022 - Elsevier
Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

[HTML][HTML] Anti-inflammatory and anticancer effects of microalgal carotenoids

J Ávila-Román, S García-Gil, A Rodríguez-Luna… - Marine Drugs, 2021 - mdpi.com
Acute inflammation is a key component of the immune system's response to pathogens, toxic
agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing …

[HTML][HTML] Fucoxanthin from microalgae Phaeodactylum tricornutum inhibits pro-inflammatory cytokines by regulating both NF-κB and NLRP3 inflammasome activation

AH Lee, HY Shin, JH Park, SY Koo, SM Kim… - Scientific reports, 2021 - nature.com
Pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α are mediated by the activation of
various kinds of signaling pathways in the innate immune system. Particularly, NF-κB and …

[HTML][HTML] Fucoxanthin: A promising phytochemical on diverse pharmacological targets

M Mumu, A Das, TB Emran, S Mitra, F Islam… - Frontiers in …, 2022 - frontiersin.org
Fucoxanthin (FX) is a special carotenoid having an allenic bond in its structure. FX is
extracted from a variety of algae and edible seaweeds. It has been proved to contain …

[HTML][HTML] Marine pharmacology in 2016–2017: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and …

AMS Mayer, AJ Guerrero, AD Rodríguez… - Marine drugs, 2021 - mdpi.com
The review of the 2016–2017 marine pharmacology literature was prepared in a manner
similar as the 10 prior reviews of this series. Preclinical marine pharmacology research …

[HTML][HTML] Advances in fucoxanthin research for the prevention and treatment of inflammation-related diseases

B Guan, K Chen, Z Tong, L Chen, Q Chen, J Su - Nutrients, 2022 - mdpi.com
Owing to its unique structure and properties, fucoxanthin (FX), a carotenoid, has attracted
significant attention. There have been numerous studies that demonstrate FX's anti …

[HTML][HTML] Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis

J Su, K Guo, M Huang, Y Liu, J Zhang, L Sun… - Frontiers in …, 2019 - frontiersin.org
Background: Fucoxanthin (FX), a xanthophyll pigment which occurs in marine brown algae
with remarkable biological properties, has been proven to be safe for consumption by …

Anti-neuroinflammatory effects of fucoxanthin via inhibition of Akt/NF-κB and MAPKs/AP-1 pathways and activation of PKA/CREB pathway in lipopolysaccharide …

D Zhao, SH Kwon, YS Chun, MY Gu, HO Yang - Neurochemical Research, 2017 - Springer
Microglia play a critical role in controlling the homeostasis of the brain, but over-activated
microglia secrete pro-inflammatory mediators and cytokines, which induce neuronal cell …

[HTML][HTML] Fucoxanthin and rosmarinic acid combination has anti-inflammatory effects through regulation of NLRP3 inflammasome in UVB-exposed HaCaT …

A Rodríguez-Luna, J Ávila-Román, H Oliveira… - Marine drugs, 2019 - mdpi.com
Excessive exposure to ultraviolet (UV) radiation is the main risk factor to develop skin
pathologies or cancer because it encourages oxidative condition and skin inflammation. In …