From multi-omics approaches to personalized medicine in myocardial infarction
Myocardial infarction (MI) is a prevalent cardiovascular disease characterized by myocardial
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …
AMPK signalling pathway: a potential strategy for the treatment of heart failure with Chinese medicine
C Liu, X Guo, Y Zhou, H Wang - Journal of inflammation research, 2023 - Taylor & Francis
Heart failure (HF) is a complex clinical syndrome that represents the advanced stage of
cardiovascular disease, characterized by systolic and diastolic dysfunction of the heart …
cardiovascular disease, characterized by systolic and diastolic dysfunction of the heart …
Linggui Zhugan decoction delays ventricular remodeling in rats with chronic heart failure after myocardial infarction through the Wnt/β-catenin signaling pathway
Abstract Context Traditional Chinese medicine plays an important role in the prevention and
treatment of heart failure (HF). Linggui Zhugan decoction has been approved for clinical …
treatment of heart failure (HF). Linggui Zhugan decoction has been approved for clinical …
[HTML][HTML] The potential of herbal drugs to treat heart failure: The roles of Sirt1/AMPK
T Zhang, L Xu, X Guo, H Tao, Y Liu, X Liu… - Journal of …, 2023 - Elsevier
Heart failure (HF) is a highly morbid syndrome that seriously affects the physical and mental
health of patients and generates an enormous socio-economic burden. In addition to cardiac …
health of patients and generates an enormous socio-economic burden. In addition to cardiac …
[HTML][HTML] Explore the action mechanism of Danggui Buxue Decoction on chronic heart failure in rats by proteomics and untargeted metabolomics
Y Zhou, Y Guan, S Tao, Z Pu, K Yang, J Qi… - Journal of Traditional …, 2024 - Elsevier
Abstract Background and aim Danggui Buxue Decoction (DBD) has been applied to
alleviate chronic heart failure (CHF) in clinics, however, its mechanism is still unclear. This …
alleviate chronic heart failure (CHF) in clinics, however, its mechanism is still unclear. This …
[HTML][HTML] Programmed death of cardiomyocytes in cardiovascular disease and new therapeutic approaches
K Cai, H Jiang, Y Zou, C Song, K Cao, S Chen… - Pharmacological …, 2024 - Elsevier
Cardiovascular diseases (CVDs) have a complex pathogenesis and pose a major threat to
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …
Research progress of AMP-activated protein kinase and cardiac aging
Z Qiu, Y Li, Y Fu, Y Yang - Open Life Sciences, 2023 - degruyter.com
The process of aging is marked by a gradual deterioration in the physiological functions and
functional reserves of various tissues and organs, leading to an increased susceptibility to …
functional reserves of various tissues and organs, leading to an increased susceptibility to …
Clinical evidence and potential mechanisms of traditional Chinese medicine for refractory heart failure: a literature review and perspectives
L Guo, Z Yang, W Feng, Y Liu, Z Li… - Frontiers in …, 2024 - frontiersin.org
Refractory heart failure (RHF), or end-stage heart failure, has a poor prognosis and high
case fatality rate, making it one of the therapeutic difficulties in the cardiovascular field …
case fatality rate, making it one of the therapeutic difficulties in the cardiovascular field …
Omaveloxolone ameliorates isoproterenol-induced pathological cardiac hypertrophy in mice
X Li, Y Wu, Y Yang, Y Wu, X Yu, W Hu - Free Radical Research, 2024 - Taylor & Francis
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcriptional regulator that
plays a protective role against various cardiovascular diseases. Omaveloxolone is a newly …
plays a protective role against various cardiovascular diseases. Omaveloxolone is a newly …
Protective effects of METRNL overexpression against pathological cardiac remodeling
H Cao, Y Liao, J Hong - Gene, 2024 - Elsevier
At present, meteorin-like protein (METRNL) has been proven to be widely expressed in the
myocardium and participates in the pathogenic process of various cardiovascular diseases …
myocardium and participates in the pathogenic process of various cardiovascular diseases …