Cluster of differentiation 24 (CD24) is a small, highly glycosylated cell adhesion protein that
is normally expressed by immune as well as epithelial, neural, and muscle cells. Tumor …

In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most
abundant immune cells, which act as a key regulator in tumorigenesis and progression …

Recent advances in cancer immunology have enabled the discovery of promising
immunotherapies for various malignancies that have shifted the cancer treatment paradigm …

Malignant tumors are complex structures composed of cancer cells and tumor
microenvironmental cells. In this complex structure, cells cross-talk and interact, thus jointly …

Modulation of immune responses through immune checkpoint blockade has revolutionized
cutaneous melanoma treatment. However, it is still the case that not all patients respond …

The characteristic genetic abnormality of neuroendocrine neoplasms (NENs), a
heterogeneous group of tumors found in various organs, remains to be identified. Here …

Background Disulfidptosis, an emerging type of programmed cell death, plays a pivotal role
in various cancer types, notably impacting the progression of kidney renal clear cell …

Microglia play a crucial role in a range of neuropathologies through exacerbated activation.
Microglial inflammatory responses can be influenced by prior exposures to noxious stimuli …

Tumor cells release exosomes, extracellular vesicle containing various bioactive molecules
such as protein, DNA and RNA. The analysis of RNA molecules packaged in exosomes may …

Siglecs belong to a family of immune regulatory receptors predominantly found on
hematopoietic cells. They interact with Sia, resulting in the activation or inhibition of the …