[HTML][HTML] Immunotherapy for hepatocellular carcinoma: current status and future prospects

Z Liu, X Liu, J Liang, Y Liu, X Hou, M Zhang… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer with poor
prognosis. Surgery, chemotherapy, and radiofrequency ablation are three conventional …

First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management and future challenges

A Rizzo, AD Ricci, G Gadaleta-Caldarola… - Expert Review of …, 2021 - Taylor & Francis
Introduction Immunotherapy has recently taken on an extremely important role in medical
oncology, as first-or later-line treatment in several tumor types, and recent years have seen …

[HTML][HTML] The immunosuppressive microenvironment and immunotherapy in human glioblastoma

X Zhang, L Zhao, H Zhang, Y Zhang, H Ju… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma multiforme (GBM) is the most malignant intracranial tumor in adults,
characterized by extensive infiltrative growth, high vascularization, and resistance to multiple …

[HTML][HTML] Neoantigen vaccines; clinical trials, classes, indications, adjuvants and combinatorial treatments

JVL Niemi, AV Sokolov, HB Schiöth - Cancers, 2022 - mdpi.com
Simple Summary Personalized neoantigen vaccines are a diverse group of personally
tailored cancer vaccines that strengthen patients´ own immune reaction against cancer …

Immune Cycle‐Based Strategies for Cancer Immunotherapy

Y Li, X Liu, X Zhang, W Pan, N Li… - Advanced Functional …, 2021 - Wiley Online Library
The immune system is composed of immune organs, immune cells, and immunoactive
substances, which plays a vital role in antitumor immunity in cancer immunotherapy. During …

[HTML][HTML] Non-alcoholic steatohepatitis and risk of hepatocellular carcinoma

RS Rios, KI Zheng, MH Zheng - Chinese medical journal, 2021 - journals.lww.com
The emergence of non-alcoholic fatty liver disease (NAFLD) as the leading chronic liver
disease worldwide raises some concerns. In particular, NAFLD is closely tied to sedentary …

Intercellular crosstalk of liver sinusoidal endothelial cells in liver fibrosis, cirrhosis and hepatocellular carcinoma

H Li - Digestive and Liver Disease, 2022 - Elsevier
Intercellular crosstalk among various liver cells plays an important role in liver fibrosis,
cirrhosis, and hepatocellular carcinoma (HCC). Capillarization of liver sinusoidal endothelial …

[HTML][HTML] Immunotherapies for advanced hepatocellular carcinoma

LY Sun, KJ Zhang, YM Xie, JW Liu… - Frontiers in …, 2023 - frontiersin.org
Primary liver cancer is the second leading cause of tumor-related deaths in China, with
hepatocellular carcinoma (HCC) accounting for 80%–90% of these. Since there is a lack of …

[HTML][HTML] First-line systemic treatment strategies for unresectable hepatocellular carcinoma: a systematic review and network meta-analysis of randomized clinical trials

W Liu, B Quan, S Lu, B Tang, M Li, R Chen… - Frontiers in …, 2021 - frontiersin.org
Objective Several new first-line treatments were recently approved for unresectable
hepatocellular carcinoma (HCC). In this meta-analysis, we compare the efficacy and safety …

[HTML][HTML] Veliparib and nivolumab in combination with platinum doublet chemotherapy in patients with metastatic or advanced non-small cell lung cancer: A phase 1 …

JM Clarke, JD Patel, F Robert, EA Kio, E Thara… - Lung Cancer, 2021 - Elsevier
Objectives Both combinations of the PARP inhibitor veliparib plus platinum doublet
chemotherapy (CT), and the programmed death receptor-1 (PD-1) inhibitor nivolumab plus …