Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

Perioperative immediate hypersensitivity reactions are rare. Subsequent allergy
investigation is complicated by multiple simultaneous drug exposures, the use of drugs with …

Recent data indicated a high incidence of inappropriate management of neuromuscular
block, with a high rate of residual paralysis and relaxant-associated postoperative …

Suspected perioperative allergic reactions are rare but can be life-threatening. The
diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct …

The belief that, for the individual patient, the benefit of prompt and continued use of
antimicrobials outweighs any potential harm is a significant barrier to improved stewardship …

Many adverse reactions to therapeutic drugs appear to be allergic in nature, and are thought
to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug …

Suspected perioperative hypersensitivity reactions are rare but contribute significantly to the
morbidity and mortality of surgical procedures. Recent publications have highlighted the …

Cardiac arrest in the peri‐operative period is rare but associated with significant morbidity
and mortality. Current reporting systems do not capture many such events, so there is an …

Background Anaphylaxis during anaesthesia is a serious complication for patients and
anaesthetists. There is little published information on management and outcomes of …

Paired acute and baseline serum or plasma tryptase sampling and determination have
recently been included as a mechanistic approach in the diagnostic and management …