Tricking the balance: NK cells in anti-cancer immunity
J Pahl, A Cerwenka - Immunobiology, 2017 - Elsevier
Natural Killer (NK) cells are classically considered innate immune effector cells involved in
the first line of defense against infected and malignant cells. More recently, NK cells have …
the first line of defense against infected and malignant cells. More recently, NK cells have …
Memory-like NK cells: remembering a previous activation by cytokines and NK cell receptors
JHW Pahl, A Cerwenka, J Ni - Frontiers in immunology, 2018 - frontiersin.org
Natural Killer (NK) cells are cytotoxic innate lymphoid cells serving at the front line against
infection and cancer. In inflammatory microenvironments, multiple soluble and contact …
infection and cancer. In inflammatory microenvironments, multiple soluble and contact …
Innate immune cells: a potential and promising cell population for treating osteosarcoma
Z Wang, Z Wang, B Li, S Wang, T Chen… - Frontiers in …, 2019 - frontiersin.org
Advanced, recurrent, or metastasized osteosarcomas remain challenging to cure or even
alleviate. Therefore, the development of novel therapeutic strategies is urgently needed …
alleviate. Therefore, the development of novel therapeutic strategies is urgently needed …
Sequencing overview of Ewing sarcoma: a journey across genomic, epigenomic and transcriptomic landscapes
LGL Sand, K Szuhai, PCW Hogendoorn - International journal of …, 2015 - mdpi.com
Ewing sarcoma is an aggressive neoplasm occurring predominantly in adolescent
Caucasians. At the genome level, a pathognomonic EWSR1-ETS translocation is present …
Caucasians. At the genome level, a pathognomonic EWSR1-ETS translocation is present …
Circular RNAs hsa_circ_0032462, hsa_circ_0028173, hsa_circ_0005909 are predicted to promote CADM1 expression by functioning as miRNAs sponge in human …
Background Osteosarcoma (OS) is a primary malignant bone tumor with a high fatality rate.
Many circRNAs have been proved to play important roles in the pathogenesis of some …
Many circRNAs have been proved to play important roles in the pathogenesis of some …
[HTML][HTML] Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma
B Li, X Zhu, L Sun, L Yuan, J Zhang, H Li, Z Ye - Oncotarget, 2014 - ncbi.nlm.nih.gov
Conventional non-surgical therapeutic regimens against osteosarcoma are subject to
chemoresistance and tumor relapse, and immunotherapy may be promising for this tumor …
chemoresistance and tumor relapse, and immunotherapy may be promising for this tumor …
Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural …
GH Boerman, MM van Ostaijen-ten Dam… - Cancer Immunology …, 2015 - Springer
Children with advanced stages (relapsed/refractory and stage IV) of rhabdomyosarcoma
(RMS) have a poor prognosis despite intensive chemotherapy and autologous stem cell …
(RMS) have a poor prognosis despite intensive chemotherapy and autologous stem cell …
A novel treatment for Ewing's sarcoma: chimeric antigen receptor-T cell therapy
Z Lin, Z Wu, W Luo - Frontiers in Immunology, 2021 - frontiersin.org
Ewing's sarcoma (EWS) is a malignant and aggressive tumor type that predominantly occurs
in children and adolescents. Traditional treatments such as surgery, radiotherapy and …
in children and adolescents. Traditional treatments such as surgery, radiotherapy and …
NK-cell-dependent killing of colon carcinoma cells is mediated by natural cytotoxicity receptors (NCRs) and stimulated by parvovirus infection of target cells
R Bhat, J Rommelaere - BMC cancer, 2013 - Springer
Background Investigating how the immune system functions during malignancies is crucial
to developing novel therapeutic strategies. Natural killer (NK) cells, an important component …
to developing novel therapeutic strategies. Natural killer (NK) cells, an important component …
Prospects for NK cell therapy of sarcoma
Simple Summary Sarcomas are a group of aggressive tumors originating from mesenchymal
tissues. Patients with advanced disease have poor prognosis due to the ineffectiveness of …
tissues. Patients with advanced disease have poor prognosis due to the ineffectiveness of …