From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer

MS Hussain, ASA Altamimi, M Afzal, I Kazmi… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

NSD3: Advances in cancer therapeutic potential and inhibitors research

S Xiu, X Chi, Z Jia, C Shi, X Zhang, Q Li, T Gao… - European Journal of …, 2023 - Elsevier
Nuclear receptor-binding SET domain 3, otherwise known as NSD3, is a member of the
group of lysine methyltransferases and is involved in a variety of cellular processes …

mTOR Signaling: Recent Progress

AN Gargalionis, KA Papavassiliou… - International Journal of …, 2024 - mdpi.com
In the intricate landscape of human biology, the mechanistic target of rapamycin (mTOR)
emerges as a key regulator, orchestrating a vast array of processes in health and disease …

Hair follicle stem cells promote epidermal regeneration under expanded condition

Y Zhang, J Cui, Z Cang, J Pei, X Zhang, B Song… - Frontiers in …, 2024 - frontiersin.org
Skin soft tissue expansion is the process of obtaining excess skin mixed with skin
development, wound healing, and mechanical stretching. Previous studies have reported …

mTOR signaling in hair follicle and hair diseases: recent progress

W Tu, YW Cao, M Sun, Q Liu, HG Zhao - Frontiers in Medicine, 2023 - frontiersin.org
Mammalian target of rapamycin (mTOR) signaling pathway is a major regulator of cell
proliferation and metabolism, playing significant roles in proliferation, apoptosis …

Paxbp1 is indispensable for the maintenance of peripheral CD4 T cell homeostasis

W Li, Y Yang, F Zhuo, S Liu, K Zhang, W Zhang… - …, 2024 - Wiley Online Library
The size and condition of the peripheral CD4 T cell population determine the capacity of the
immune response. Under homeostatic conditions, the size of the peripheral CD4 T cell …

Everolimus-induced hyperpermeability of endothelial cells causes lung injury

X Chen, J Chen, S Liu, X Li - Experimental Biology and …, 2023 - journals.sagepub.com
The mammalian target of rapamycin (mTOR) inhibitors, everolimus (but not dactolisib), is
frequently associated with lung injury in clinical therapies. However, the underlying …

Structural Insights into the Giardia lamblia Target of Rapamycin Homolog: A Bioinformatics Approach

PLA Muñoz-Muñoz, RE Mares-Alejandre… - International Journal of …, 2023 - mdpi.com
TOR proteins, also known as targets of rapamycin, are serine/threonine kinases involved in
various signaling pathways that regulate cell growth. The protozoan parasite Giardia lamblia …