Background Due to the complexity of the mechanisms involved in epileptogenesis, the
available antiseizure drugs (ASDs) do not meet clinical needs; hence, both the discovery of …

Conclusions The CF has recently emerged as one of the most phenotypically plastic cells in
the heart, with distinct transcriptional and secretory programs that regulate their essential …

Abstract Purpose of Review To summarize the current knowledge on the role that B
lymphocytes play in heart failure. Recent Findings Several studies from murine models have …

Background Heart failure (HF) is a major cause of death worldwide. The most effective
treatment for HF is heart transplantation, but its use is limited by the scarcity of donor hearts …

Opinion statement Cancer patients who receive high-dose thoracic radiotherapy may
develop radiation-induced heart disease (RIHD). The clinical presentation of RIHD …

Fabry disease (FD) is a lysosomal disorder caused by α-galactosidase A deficiency,
resulting in the accumulation of globotriaosylceramide (Gb-3) and its metabolite …

Myocardial infarction (MI) is defined as evidence of myocardial necrosis consistent with
prolonged ischemia. In response to MI, the myocardium undergoes a series of wound …

Background With an increasing number of myocardial infarction (MI) patients, myocardial
fibrosis is becoming a widespread health concern. It's becoming more and more urgent to …

Fibrosis, characterized by an excessive accumulation of extracellular matrix, has long been
seen as an adaptive process that contributes to tissue healing and regeneration. More …

The heart contains an abundant fibroblast population that may play a role in homeostasis, by
maintaining the extracellular matrix (ECM) network, by regulating electrical impulse …