Nowadays, diabetes mellitus (DM) and hypertension are considered as the most common
causes of end-stage renal disease (ESRD). In this paper, other than presenting the role of …

Membranous nephropathy is a frequent cause of nephrotic syndrome in adults. In most
patients, it appears as a primary renal disease but in about 20% of cases membranous …

The diagnostic performance of M-type phospholipase A2 receptor (PLA2R) autoantibodies
and PLA2R glomerular staining in discriminating between idiopathic membranous …

Background and objectives The research work in the past years showed that detection of
phospholipase A2 receptor (PLA2R) antigen and its dominant IgG4 autoantibody in …

Background: M-type phospholipase A2 Receptor is known as a major antigen on podocytes
which is involved with the pathogenesis of idiopathic membranous nephropathy (iMN). Many …

Aim Recent studies have revealed that anti-phospholipase A2 receptor antibodies (aPLA2R-
ABs) may play a role in the diagnosis of idiopathic membranous nephropathy (IMN). We will …

Background: Anti-phospholipase A2 receptor (PLA2R) antibodies are specific to the
diagnosis of primary membranous nephropathy (pMN). The prevalence of positive …

The majority of cases of primary membranous nephropathy (MN) are associated with auto-
antibodies against the podocyte antigen M-type phospholipase A2 receptor (PLA2R). This …

To investigate whether the human anti-thrombospondin type 1 domain-containing 7A
(THSD7A) antibody-induced membranous nephropathy (MN) is mediated by activating lectin …

Abstract Background Although IgG4 deposit against phospholipase A2 receptor (anti-
PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous …