The strategies involved in the development of therapeutics for neurodegenerative disorders
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …

Delphi is a scientific method to organize and structure an expert discussion aiming to
generate insights on controversial topics with limited information. The technique has seen a …

Background The number of individuals living with dementia is increasing, negatively
affecting families, communities, and health-care systems around the world. A successful …

Type 2 diabetes and cognitive dysfunction are highly prevalent disorders worldwide.
Although type 2 diabetes is associated with an increased risk of dementia, awareness of the …

Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly
recognised as global health priorities in view of the preventability of most injuries and the …

Growing evidence suggests that fine particulate matter (PM2. 5) likely increases the risks of
dementia, yet little is known about the relative contributions of different constituents. Here …

Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …

In this paper, we explore the utility of resting-state EEG measures as potential biomarkers for
the detection and assessment of cognitive decline in mild cognitive impairment (MCI) and …

Sleep disturbances and dementia are two common and significant health problems in older
adults. Investigations suggest that sleep disturbances might increase the risk of dementia …