Neuroendocrine differentiation (NED) in prostate cancer is a well-recognized phenotypic
change by which prostate cancer cells transdifferentiate into neuroendocrine-like (NE-like) …

High dose-rate (HDR) brachytherapy involves delivery of a high dose of radiation to the
cancer with great sparing of surrounding organs at risk. Prostate cancer is thought to be …

Purpose To report the primary endpoint of biochemical progression-free survival (b-PFS)
and secondary survival endpoints from ASCENDE-RT, a randomized trial comparing 2 …

Purpose To report the genitourinary (GU) and gastrointestinal (GI) morbidity and erectile
dysfunction in a randomized trial comparing 2 methods of dose escalation for high-and …

Background and purpose Multi-fraction high dose-rate (HDR) brachytherapy as
monotherapy is safe and effective for low and intermediate risk prostate cancer. Two or …

Brachytherapy has become an essential pillar in all-stages of localized prostate cancer,
where dose escalation has been demonstrated to improve outcome. HDR brachytherapy …

Purpose Ultrasound (US)‐guided high dose rate (HDR) prostate brachytherapy requests the
clinicians to place HDR needles (catheters) into the prostate gland under transrectal US …

Purpose To review outcomes for high-risk prostate cancer treated with combined modality
radiation therapy (CMRT) utilizing external beam radiation therapy (EBRT) with a …

Radiotherapy (RT) for prostate cancer (PC) has steadily evolved over the last decades, with
improving biochemical disease‐free survival. Recently population based research also …

Aims To report health-related quality of life (HRQOL) and toxicity in prostate cancer patients
treated with single-fraction high dose rate (HDR) brachytherapy boost and external beam …