Scaffold attachment factor A (SAF-A) or hnRNP U is a nuclear RNA-binding protein with a
well-documented role in processing newly transcribed RNA. Recent studies also indicate …

Unlike bulk materials, nanomaterials have unique properties that make them suitable for
biosensor applications. Nanomaterial-based biosensors have a series of advantages that …

With the development of super-resolution imaging techniques, it is crucial to understand
protein structure at the nanoscale in terms of clustering and organization in a cell. However …

Homogeneous illumination in single-molecule localization microscopy (SMLM) is key for the
quantitative analysis of super-resolution images. Therefore, different approaches for flat-field …

Quantitative characterization of protein abundance and interactions in live cells is necessary
to understand and predict cellular behavior. The accurate determination of copy number for …

Single molecule localization microscopy has become a prominent technique to
quantitatively study biological processes below the optical diffraction limit. By fitting the …

Heterogeneous nuclear ribonucleoprotein U (HNRNPU) is a nuclear protein that plays a
crucial role in various biological functions, such as RNA splicing and chromatin …

The genome is packed into the cell nucleus in the form of chromatin. Biochemical
approaches have revealed that chromatin is packed within domains, which group into larger …

In recent years, intrinsically disordered regions have been identified as a common feature of
RNA-binding proteins in eukaryotes ranging from humans to yeast. This challenges previous …

Single-molecule localization microscopy resolves objects below the diffraction limit of light
via sparse, stochastic detection of target molecules. Single molecules appear as clustered …