Gentiopicroside ameliorates bleomycin-induced pulmonary fibrosis in mice via inhibiting inflammatory and fibrotic process

C Chen, Y Wang, Y Wang, M Cheng, J Yin… - Biochemical and …, 2018 - Elsevier
Pulmonary fibrosis (PF) is a chronic and ultimately fatal interstitial lung disease of various
causes. The advent of nintedanib and pirfenidone provides treatment options for PF patients …

A metabolomic approach to elucidate the inhibitory effects of baicalin in pulmonary fibrosis

H Chang, H Meng, W Bai, Q Meng - Pharmaceutical Biology, 2021 - Taylor & Francis
Context Baicalin, a major flavonoid extracted from Scutellaria baicalensis Georgi
(Lamiaceae), has been shown to exert therapeutic effects on pulmonary fibrosis (PF) …

Interstitial lung disease

V Cottin - European Respiratory Review, 2013 - Eur Respiratory Soc
This article reviews the most important articles published in interstitial lung disease, as
reviewed during the Clinical Year in Review session at the 2012 annual European …

Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits

SH Kim, J Kim, JY Jang, H Noh, J Park… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus
disease 2019 (COVID-19) has been a global health concern since 2019. The viral spike …

Naringenin: a promising therapeutic agent against organ fibrosis

Y Du, J Ma, Y Fan, X Wang, S Zheng… - Oxidative medicine …, 2021 - Wiley Online Library
Fibrosis is the final common pathology of most chronic diseases as seen in the heart, liver,
lung, kidney, and skin and contributes to nearly half of death in the developed countries …

[HTML][HTML] Prevention of bleomycin-induced pulmonary inflammation and fibrosis in mice by paeonol

MH Liu, AH Lin, HK Ko, DW Perng, TS Lee… - Frontiers in …, 2017 - frontiersin.org
Pulmonary fibrosis is a severe and progressive disease that is characterized by an abnormal
deposition of extracellular matrix, such as collagens. The pathogenesis of this disease may …

Time-resolved proteome and transcriptome of paraquat-induced pulmonary fibrosis

L Fan, Y Li, X Zhang, Y Wu, Y Song, F Zhang… - Pulmonary …, 2022 - Elsevier
Backgrounds Pulmonary fibrosis (PF) is a pathological state presenting at the progressive
stage of heterogeneous interstitial lung disease (ILD). The current understanding of the …

Single‐cell rNA sequencing reveals the interaction of injected ADSCs with lung‐originated cells in mouse pulmonary fibrosis

M Rahman, ZY Wang, JX Li, HW Xu… - Stem Cells …, 2022 - Wiley Online Library
Pulmonary fibrosis (PF) is a severe chronic lung disease with little effective treatment options
other than lung transplantation. Adipose‐derived mesenchymal stem cells (ADSCs) have …

Polyhexamethylene guanidine phosphate-induced ROS-mediated DNA damage caused cell cycle arrest and apoptosis in lung epithelial cells

JS Park, YJ Park, HR Kim, KH Chung - The Journal of toxicological …, 2019 - jstage.jst.go.jp
Polyhexamethylene guanidine phosphate (PHMG-p) is an active ingredient of humidifier
disinfectants and causes severe lung injury resulting in pulmonary fibrosis. Current evidence …

Protective effect of dimethyl itaconate against fibroblast–myofibroblast differentiation during pulmonary fibrosis by inhibiting TXNIP

YY Han, X Gu, CY Yang, HM Ji, YJ Lan… - Journal of cellular …, 2021 - Wiley Online Library
Fibroblast–myofibroblast differentiation (FMD) is a critical cellular phenotype during the
occurrence and deterioration of pulmonary fibrosis (PF). FMD can increase with an elevated …