Abstract Background Jinshui Huanxian formula (JHF) ameliorates idiopathic pulmonary
fibrosis patients. Active compounds, including icariin, isoliquiritigenin, nobiletin, peimine …

Paraquat (PQ) is a widely used herbicide indeveloping countries worldwide, and pulmonary
fibrosis is one of the most typical features of PQ poisoning. The molecular mechanism of PQ …

Background Small leucine-rich proteoglycans (SLRPs) are molecules that have signaling
roles in a multitude of biological processes. In this respect, SLRPs play key roles in the …

Viruses are intracellular pathogen that exploit host cellular machinery for their propagation.
Extensive research on virus-host interaction have shed light on an alternative antiviral …

Secreted Frizzled Receptor Protein 4 (SFRP4) has been shown to be increased in
Scleroderma (SSc). To determine its role in immune-driven fibrosis, we analysed SSc and …

To investigate the inhibitory effects of chlorogenic acid on pulmonary fibrosis and the
internal mechanisms in vivo and in vitro. 30 male BALB/C mice were randomized into 5 …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no
effective medical therapies. Recent research has focused on identifying the biological …

Pulmonary fibrosis is characterized by an extensive activation of fibrogenic cells and
deposition of extracellular matrix (ECM). Transforming growth factor (TGF)‐β1 plays a pivotal …

Pulmonary fibrosis is the end stage of many interstitial lung diseases, characterized by the
deposition of excess extracellular matrix (ECM), destruction of normal alveolar structure, and …

Background Idiopathic pulmonary fibrosis (IPF), a chronic, progressive, fibrosing interstitial
lung disease, is associated with extremely poor prognosis, and lacks effective treatment. The …