[HTML][HTML] miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

miRNAs orchestration of cardiovascular diseases-Particular emphasis on diagnosis, and progression

EGE Elsakka, AI Abulsoud, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in
regulating gene expression. They are significant in many biological and pathological …

[HTML][HTML] Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases

Y Liu, W Ding, J Wang, X Ao, J Xue - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

[HTML][HTML] Modulation of NRF2/KEAP1 signaling in preeclampsia

G Tossetta, S Fantone, F Piani, C Crescimanno… - Cells, 2023 - mdpi.com
Placentation is a key and tightly regulated process that ensures the normal development of
the placenta and fetal growth. Preeclampsia (PE) is a hypertensive pregnancy-related …

[HTML][HTML] Adverse cardiac remodelling after acute myocardial infarction: old and new biomarkers

AE Berezin, AA Berezin - Disease Markers, 2020 - hindawi.com
The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial
infarction (AMI) does not decrease regardless of implementation of new technologies …

[HTML][HTML] miRNA dysregulation in cardiovascular diseases: current opinion and future perspectives

F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …

[HTML][HTML] Targeting the microRNA-34a as a novel therapeutic strategy for cardiovascular diseases

CC Hua, XM Liu, LR Liang, LF Wang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are still the main cause of morbidity and mortality
worldwide and include a group of disorders varying from vasculature, myocardium …

The role of microRNA in the development, diagnosis, and treatment of cardiovascular disease: recent developments

A Wronska - Journal of Pharmacology and Experimental …, 2023 - ASPET
Since their discovery in 1993, microRNAs (miRNAs) have emerged as important regulators
of many crucial cellular processes, and their dysregulation have been shown to contribute to …

[HTML][HTML] Cardiac aging: from basic research to therapeutics

M Yan, S Sun, K Xu, X Huang, L Dou, J Pang… - … medicine and cellular …, 2021 - hindawi.com
With research progress on longevity, we have gradually recognized that cardiac aging
causes changes in heart structure and function, including progressive myocardial …

[HTML][HTML] Functional role of microRNAs in regulating cardiomyocyte death

U Kansakar, F Varzideh, P Mone, SS Jankauskas… - Cells, 2022 - mdpi.com
microRNAs (miRNA, miRs) play crucial roles in cardiovascular disease regulating numerous
processes, including inflammation, cell proliferation, angiogenesis, and cell death. Herein …