Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a
molecular lynchpin that links persistent infections and chronic inflammation to increased …

The pathogenesis of inflammatory bowel disease (IBD) is still unclear. Immune dysfunction
may play a key role in the pathogenesis of IBD, in which the role of CD4+ T helper (Th) cells …

Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung disease with no
established treatment and is characterized by progressive scarring of the lung tissue and an …

The view of CD4 T‐cell‐mediated immunity as a balance between distinct lineages of Th1
and Th2 cells has changed dramatically. Identification of the IL‐17 family of cytokines and of …

Endometriosis is a chronic, inflammatory disease characterized by the growth of endometrial
tissue in aberrant locations outside the uterus. Neoangiogenesis or establishment of new …

Periodontitis (PD) is a chronic inflammatory disease characterised by tissue inflammation
and destruction of the associated alveolar bone. It is caused by the colonisation of the …

Although the microbiota has been shown to drive production of interleukin-17A (IL-17A) from
T helper 17 cells to promote cell proliferation and tumor growth in colorectal cancer, the …

Endometriosis refers to the growth of ectopic endometrial tissue outside the uterine cavity.
About 10–15% of female in reproductive age suffer from endometriosis. Several etiologies …

Background: The IL-17 (interleukin 17) family consists of six structurally related pro-
inflammatory cytokines, namely IL-17A to IL-17F. These cytokines have garnered significant …