Background Although frailty has been associated with increased risks for hospitalization and
mortality in chronic heart failure, the precise average effect remains uncertain. We performed …

Background: The semiquantitative Clinical Frailty Scale (CFS) is a simple tool to assess
patients' frailty and has been shown to correlate with mortality in elderly patients even when …

Frailty is common and associated with poorer outcomes in the elderly, but its role as
potential cardiovascular disease (CVD) risk factor requires clarification. We thus aimed to …

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality. With the
ageing population, the prognostic determinants among others include frailty, health status …

Mitral regurgitation (MR) is one of the most prevalent valve disorders and has numerous
aetiologies, including primary (organic) MR, due to underlying degenerative/structural mitral …

Transcatheter aortic valve replacement (TAVR) is an effective treatment for severe
symptomatic aortic stenosis (AS) in patients who are inoperable or at high risk for surgery …

Transcatheter aortic valve implantation (TAVI) has spawned the evolution of novel catheter-
based therapies for a variety of cardiovascular conditions. Newer device iterations are …

Frailty is a geriatric syndrome characterised by a vulnerability status associated with
declining function of multiple physiological systems and loss of physiological reserves. Two …

Background: A differential impact of sex has been observed in transcatheter aortic valve
replacement (TAVR) outcomes from small observational studies and subgroup analyses of …

Background Elective surgeries can be associated with significant harm to older adults. The
present study aimed to identify the prognostic factors associated with the development of …