[HTML][HTML] PLGA-Based Nanomedicine: History of Advancement and Development in Clinical Applications of Multiple Diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

[HTML][HTML] Matrix Metalloproteinases in Chronic Obstructive Pulmonary Disease

ME Christopoulou, E Papakonstantinou… - International Journal of …, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade proteins of the
extracellular matrix and the basement membrane. Thus, these enzymes regulate airway …

[HTML][HTML] Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary

A Agustí, BR Celli, GJ Criner, D Halpin… - American journal of …, 2023 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published the
complete 2023 GOLD report, which can be freely downloaded from its web page (www …

The impact of war on the environment and health: implications for readiness, response, and recovery in Ukraine

F Racioppi, H Rutter, D Nitzan, A Borojevic, Z Carr… - The Lancet, 2022 - thelancet.com
Since the Russian invasion began on Feb 24, 2022, Ukraine has suffered a dramatic
escalation of a humanitarian, health, and environmental emergency, spurring the most rapid …

[HTML][HTML] The Tobacco Smoke Component, Acrolein, as a Major Culprit in Lung Diseases and Respiratory Cancers: Molecular Mechanisms of Acrolein Cytotoxic …

P Hikisz, D Jacenik - Cells, 2023 - mdpi.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …

An update on outcomes for COPD pharmacological trials: a COPD investigators report-reassessment of the 2008 American Thoracic Society/European Respiratory …

M Cazzola, P Rogliani, PJ Barnes, F Blasi… - American Journal of …, 2023 - atsjournals.org
Background: In 2008, a dedicated American Thoracic Society/European Respiratory Society
task force published a paper on the possible use and limitations of clinical outcomes and …

Current progress of copd early detection: Key points and novel strategies

CH Lin, SL Cheng, CZ Chen, CH Chen… - … Journal of Chronic …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide, with approximately 70% to 80% of adults with COPD being undiagnosed …

Variability of fractional exhaled nitric oxide is associated with the risk and aetiology of COPD exacerbations

DM Schumann, E Papakonstantinou, K Kostikas… - …, 2023 - Wiley Online Library
Abstract Background and Objective Acute exacerbations of chronic obstructive pulmonary
disease (AECOPD) are heterogeneous in aetiology and accelerate disease progression …

Classification of COPD: fostering prevention and precision medicine in the Lancet Commission on COPD

GG Brusselle, M Humbert - The Lancet, 2022 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a highly prevalent and heterogeneous
chronic disease of the lower airways and lungs that is associated with huge morbidity …

Contemporary concise review 2022: chronic obstructive pulmonary disease

PMA Calverley, PP Walker - Respirology, 2023 - Wiley Online Library
SUMMARY OF KEY POINTS International respiratory organizations now recommend using
lower limit of normal and standardized residuals to diagnose airflow obstruction and COPD …