Patient-reported outcomes in cancer clinical trials: measuring symptomatic adverse events with the National Cancer Institute's Patient-Reported Outcomes Version of …

PG Kluetz, DT Chingos, EM Basch… - American Society of …, 2016 - ascopubs.org
Systematic capture of the patient perspective can inform the development of new cancer
therapies. Patient-reported outcomes (PROs) are commonly included in cancer clinical trials; …

Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies

G Thanarajasingam, LM Minasian, F Baron… - The Lancet …, 2018 - thelancet.com
Tremendous progress in treatment and outcomes has been achieved across the whole
range of haematological malignancies in the past two decades. Although cure rates for …

Immune checkpoint inhibitors side effects and management

HR Kourie, J Klastersky - Immunotherapy, 2016 - Future Medicine
The next decade in cancer therapy will be marked by the expansion of immunotherapies,
namely immune checkpoint inhibitors. The increasing number and combination of …

Side-effects of checkpoint inhibitor-based combination therapy

HR Kourie, JA Klastersky - Current opinion in oncology, 2016 - journals.lww.com
Despite the high toxicity rates observed with some checkpoint inhibitor-based combination
therapies, these combinations will likely become the new paradigm for the management of …

Risk of adverse events with the addition of targeted agents to endocrine therapy in patients with hormone receptor-positive metastatic breast cancer: a systematic …

S Martel, M Bruzzone, M Ceppi, C Maurer… - Cancer treatment …, 2018 - Elsevier
Background Combining targeted agents and endocrine therapy (ET) improves outcomes in
hormone receptor-positive metastatic breast cancer patients but increases the risk of …

[HTML][HTML] Challenges and countermeasures of thoracic oncology in the epidemic of COVID-19

H Guo, X Chen, C Su, Y Liu, H Wang… - … lung cancer research, 2020 - ncbi.nlm.nih.gov
Abstract Since December, 2019, a 2019 novel coronavirus disease (COVID-19) infected by
the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) emerged in Wuhan …

[HTML][HTML] Toward the clonotype analysis of alopecia areata-specific, intralesional human CD8+ T lymphocytes

M Bertolini, Y Uchida, R Paus - Journal of Investigative Dermatology …, 2015 - Elsevier
Alopecia areata (AA) is an organ-restricted autoimmune disease that mainly affects the hair
follicle (HF). Several findings support a key primary effector role of CD8+ T cells in the …

Entwicklung einer österreichischen Forschungsagenda für onkologische Pflege

R Silvia, KH Sabine, H Mayer - HeilberufeSCIENCE, 2017 - search.proquest.com
Hintergrund Pflegeforschung ist eine wesentliche Komponente bei der Verbesserung der
Versorgung onkologisch erkrankter Menschen. Da der Forschungsbedarf hoch ist und …

[PDF][PDF] LAPATINIB INDUCED-CHANGES IN CACO-2 INTESTINAL MONOLAYER VIA ERBB1 INHIBITION

RNURF SYAZA, BR SHARIN - 2023 - researchgate.net
Lapatinib (LAP) is an orally administered dual ErbB1 and ErbB2 tyrosine kinase inhibitor for
ErbB2-positive breast tumours, but is associated with diarrhoea. Incidence of lapatinib …

Long-term disease control and high clinical benefit in a patient with advanced thyroid cancer treated with lenvatinib

L Muratori, P Sperone, GV Scagliotti - Future Oncology, 2019 - Future Medicine
We report a case of a 37-year-old man with metastatic differentiated thyroid carcinoma,
previously submitted to total thyroidectomy, radio-iodine therapy and lung metastasectomy …