Overview and future potential of buccal mucoadhesive films as drug delivery systems for biologics

M Montenegro-Nicolini, JO Morales - Aaps Pharmscitech, 2017 - Springer
The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …

Nanoemulgel: A promising novel formulation for treatment of skin ailments

B Ojha, VK Jain, S Gupta, S Talegaonkar, K Jain - Polymer Bulletin, 2022 - Springer
Nanoemulgel is an emanating drug delivery system particularly being explored in research
and development of various topical formulations for both pharmaceutical and cosmeceutical …

Formulation and optimization of sodium alginate polymer film as a buccal mucoadhesive drug delivery system containing cetirizine dihydrochloride

K Pamlényi, K Kristó, O Jójárt-Laczkovich, G Regdon Jr - Pharmaceutics, 2021 - mdpi.com
Currently, pharmaceutical companies are working on innovative methods, processes and
products. Oral mucoadhesive systems, such as tablets, gels, and polymer films, are among …

Oromucosal films: From patient centricity to production by printing techniques

Y Tian, M Orlu, HJ Woerdenbag, M Scarpa… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Oromucosal films, comprising mucoadhesive buccal films (MBFs) and
orodispersible films (ODFs), are considered patient-centric dosage forms. Target groups are …

An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems

M Jug, A Hafner, J Lovrić, ML Kregar, I Pepić… - … of pharmaceutical and …, 2018 - Elsevier
In vitro dissolution/release tests are an important tool in the drug product development
phase as well as in its quality control and the regulatory approval process. Mucosal drug …

Formulation and evaluation of nano based drug delivery system for the buccal delivery of acyclovir

BE Al-Dhubiab, AB Nair, R Kumria, M Attimarad… - Colloids and Surfaces B …, 2015 - Elsevier
Oral bioavailability of acyclovir is limited, primarily because of low permeability across the
gastrointestinal membrane. The purpose of this study is the prospective evaluation of buccal …

Atorvastatin liposomes in a 3D-printed polymer film: a repurposing approach for local treatment of oral candidiasis

EM Nour, SE El-Habashy, MG Shehat… - Drug Delivery and …, 2023 - Springer
Oral candidiasis (OC) is an opportunistic fungal infection, common amongst the elderly and
the immunocompromised. Unfortunately, the therapeutic efficacy of common antifungals is …

Localized drug delivery with mono and bilayered mucoadhesive films and wafers for oral mucosal infections

SS Timur, S Yüksel, G Akca, S Şenel - International journal of …, 2019 - Elsevier
Local drug delivery into oral cavity offers many advantages over systemic administration in
treatment of the oral infections. In this study, monolayer and bilayered mucoadhesive film …

Design, Characterization, and Anticancer and Antimicrobial Activities of Mucoadhesive Oral Patches Loaded with Usnea barbata (L.) FH Wigg Ethanol Extract F-UBE …

V Popovici, E Matei, GC Cozaru, L Bucur, CE Gîrd… - Antioxidants, 2022 - mdpi.com
The oral cavity's common pathologies are tooth decay, periodontal disease, and oral cancer;
oral squamous cell carcinoma (OSCC) is the most frequent oral malignancy, with a high …

Development and evaluation of buccal films impregnated with selegiline-loaded nanospheres

BE Al-Dhubiab, AB Nair, R Kumria, M Attimarad… - Drug …, 2016 - Taylor & Francis
Poor peroral therapeutic efficiency of selegiline is primarily due to the extensive hepatic
metabolism and hence the need for an alternative route of administration. The present study …