[HTML][HTML] Small non-coding RNAs: new class of biomarkers and potential therapeutic targets in neurodegenerative disease

CN Watson, A Belli, V Di Pietro - Frontiers in genetics, 2019 - frontiersin.org
Neurodegenerative diseases (NDs) are becoming increasingly prevalent in the world, with
an aging population. In the last few decades, due to the devastating nature of these …

Fundamental neurochemistry review: Old brain stories‐Influence of age and sex on the neurodegeneration‐associated lipid changes

L Cuenca‐Bermejo, A Prinetti… - Journal of …, 2023 - Wiley Online Library
Brain aging is a naturally occurring process resulting in the decline of cognitive functions
and increased vulnerability to develop age‐associated disorders. Fluctuation in lipid species …

[HTML][HTML] Plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable Alzheimer's disease dementia in Chinese individuals

Q Sun, J Ni, M Wei, S Long, T Li, D Fan, T Lu… - Frontiers in Aging …, 2022 - frontiersin.org
Background: Plasma-derived amyloid, tau, neurodegeneration (ATN) markers can
accurately diagnose Alzheimer's disease (AD) and predict its progression. Few studies have …

Dynamic changes in central and peripheral neuro-injury vs. Neuroprotective serum markers in COVID-19 are modulated by different types of anti-viral treatments but …

K Laudanski, J Hajj, M Restrepo, K Siddiq, T Okeke… - Biomedicines, 2021 - mdpi.com
The balance between neurodegeneration, neuroinflammation, neuroprotection, and COVID-
19-directed therapy may underly the heterogeneity of SARS-CoV-2′ s neurological …

The lncRNA CCAT2 rs6983267 G allele is associated with decreased susceptibility to recurrent miscarriage

D Che, W Huang, Z Fang, L Li, H Wu… - Journal of Cellular …, 2019 - Wiley Online Library
Genetics might play various roles in susceptibility to recurrent miscarriage, and previous
studies suggest that some gene polymorphisms might be associated with abortion and …

Small RNA Sequencing in the Tg4–42 Mouse Model Suggests the Involvement of snoRNAs in the Etiology of Alzheimer's Disease

CT Lio, T Kacprowski, M Klaedtke… - Journal of …, 2022 - content.iospress.com
Background: The Tg4-42 mouse model for sporadic Alzheimer's disease (AD) has unique
features, as the neuronal expression of wild type N-truncated Aß4–42 induces an AD-typical …

PIWI-Interacting RNAs: A Pivotal Regulator in Neurological Development and Disease

X Pan, W Dai, Z Wang, S Li, T Sun, N Miao - Genes, 2024 - mdpi.com
PIWI-interacting RNAs (piRNAs), a class of small non-coding RNAs (sncRNAs) with 24–32
nucleotides (nt), were initially identified in the reproductive system. Unlike microRNAs …

PIWI-interacting RNAs in human diseases: databases and computational models

T Zhang, L Chen, R Li, N Liu, X Huang… - Briefings in …, 2022 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are short 21–35 nucleotide molecules that comprise the
largest class of non-coding RNAs and found in a large diversity of species including yeast …

[HTML][HTML] Transcriptome-wide piRNA profiling in human brains for aging genetic factors

Q Mao, L Fan, X Wang, X Lin, Y Cao… - Jacobs journal of …, 2019 - ncbi.nlm.nih.gov
Objective: Piwi-interacting RNAs (piRNAs) represent a molecular feature shared by all
nonaging biological systems, including the germline and somatic cancer stem cells, which …

Quantitative trait module-based genetic analysis of Alzheimer's disease

S Yuan, H Li, J Xie, X Sun - International Journal of Molecular Sciences, 2019 - mdpi.com
The pathological features of Alzheimer's Disease (AD) first appear in the medial temporal
lobe and then in other brain structures with the development of the disease. In this work, we …