Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging

EA van Vliet, N Marchi - Epilepsia, 2022 - Wiley Online Library
The term neurovascular unit (NVU) describes the structural and functional liaison between
specialized brain endothelium, glial and mural cells, and neurons. Within the NVU, the blood …

Recent advancement in nanosensors for neurotransmitters detection: Present and future perspective

N Chauhan, S Soni, P Agrawal, YPS Balhara… - Process Biochemistry, 2020 - Elsevier
Neurotransmitters maintain physiological condition and behaviour of the brain and body.
Studies on transmitting mechanisms and change in concentration of particular …

Experimental and molecular dynamics simulation study on the delivery of some common drugs by ZIF‐67, ZIF‐90, and ZIF‐8 zeolitic imidazolate frameworks

X Sun, M Keywanlu, R Tayebee - Applied Organometallic …, 2021 - Wiley Online Library
Anti‐seizures have been frequently used for a long time. Most of these antiepileptic drugs,
which are used on a daily basis, are central nervous system depressants, and their …

Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice

Z Zhuo, H Wang, S Zhang, PF Bartlett… - Journal of Cerebral …, 2023 - journals.sagepub.com
Despite progress in reperfusion therapy, functional recovery remains suboptimal in many
stroke patients, with oxidative stress, inflammation, dysbiosis, and secondary …

Evidence implicating blood-brain barrier impairment in the pathogenesis of acquired epilepsy following acute organophosphate intoxication

PN Bernardino, AS Luo, PM Andrew, CM Unkel… - … of Pharmacology and …, 2024 - ASPET
Organophosphate (OP) poisoning can trigger cholinergic crisis, a life-threatening toxidrome
that includes seizures and status epilepticus. These acute toxic responses are associated …

Pediatric ischemic stroke and epilepsy: a nationwide cohort study

HEK Sundelin, T Tomson, J Zelano, J Söderling… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: The risk of epilepsy after stroke has not been thoroughly explored
in pediatric ischemic stroke. We examined the risk of epilepsy in children with ischemic …

The role of inflammation in epileptogenesis

F Meng, L Yao - Acta Epileptologica, 2020 - Springer
Epilepsy is a chronic neurological disorder that has an extensive impact on a patient's life.
Accumulating evidence has suggested that inflammation participates in the progression of …

Pathogenesis of seizures and epilepsy after stroke

J Chen, H Ye, J Zhang, A Li, Y Ni - Acta Epileptologica, 2022 - Springer
Stroke is the most frequent cause of secondary epilepsy in the elderly. The incidence of
cerebral stroke is increasing with the extension of life expectancy, and the prevalence of …

The dysregulation of miRNAs in epilepsy and their regulatory role in inflammation and apoptosis

G Xie, H Chen, C He, S Hu, X Xiao, Q Luo - Functional & Integrative …, 2023 - Springer
Epilepsy is a neurological disorder that impacts millions of people worldwide, and it is
characterized by the occurrence of recurrent seizures. The pathogenesis of epilepsy is …

Neuroprotective effect of alpha-asarone on the rats model of cerebral ischemia–reperfusion stroke via ameliorating glial activation and autophagy

K Zhang, Q Liu, L Luo, X Feng, Q Hu, X Fan, S Mao - Neuroscience, 2021 - Elsevier
Alpha-asarone, a major active component isolated from Acorus gramineus, can affect brain
functions and behaviors by multiple mechanisms. However, the effect of alpha-asarone on …