Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …

Sarcopenia (severe muscle depletion) is a prevalent muscle abnormality in patients with
cirrhosis that confers poor prognosis both pre-and post-liver transplantation. The …

Cachexia is a severe complication of cancer that adversely affects the course of the disease,
with currently no effective treatments. It is characterized by a progressive atrophy of skeletal …

Background and Purpose Muscle protein catabolism in patients with diabetic nephropathy
(DN) results in striking loss of muscle proteins, which increases morbidity and mortality risks …

Oxidative stress, inflammation, mitochondrial dysfunction, reduced protein synthesis, and
increased proteolysis are all critical factors in the process of muscle atrophy. In particular …

Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced
protein synthesis/accelerated protein degradation. Various conditions, such as denervation …

Liver cancer is the second most occurring cancer worldwide and is one of the leading
causes of cancer-related deaths. Hepatocellular carcinoma (HCC) is the most common …

Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a
constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of …

Sarcopenia or muscle wasting is a progressive and generalized skeletal muscle disorder
involving the accelerated loss of muscle mass and function, often associated with muscle …

Abstract Purpose of Review Cachexia, a feature of cancer and other chronic diseases, is
marked by progressive weight loss and skeletal muscle wasting. This review aims to …