Pulmonary fibrosis comprises a wide range of fibrotic lung diseases with unknown
pathogenesis and poor prognosis. Familial pulmonary fibrosis (FPF) represents a unique …

Surfactant, which was first identified in the 1920s, is pivotal to lower the surface tension in
alveoli of the lungs and helps to lower the work of breathing and prevents atelectasis …

Children's interstitial lung disease (chILD) encompasses a wide and heterogeneous
spectrum of diseases substantially different from that of adults. Established classification …

Genetic disorders of surfactant production are rare but associated with significant morbidity
and mortality. Diagnosis can be made invasively through clinically available genetic testing …

Children's interstitial and diffuse lung disease (chILD) is a rare heterogenous group of
conditions, with symptoms often overlapping with more common conditions, impeding …

CRISPR-Cas induced homology-directed repair (HDR) enables the installation of a broad
range of precise genomic modifications from an exogenous donor template. However …

The term 'interstitial lung disease'(ILD) refers to a group of disorders involving both the
airspaces and tissue compartments of the lung, and these disorders are more accurately …

Biallelic variants in ABCA3, the gene encoding the lipid transporter ATP-binding cassette
subfamily A member 3 (ABCA3) that is predominantly expressed in alveolar type II cells, may …

ABCA3 mutations in adult pulmonary fibrosis patients: a case... : Current Opinion in
Pulmonary Medicine ABCA3 mutations in adult pulmonary fibrosis patients: a case series …

Objective To describe disease course, histopathology, and outcomes for infants with atypical
presentations of alveolar capillary dysplasia with misalignment of the pulmonary veins …