Intestinal stem cells at the bottom of crypts fuel the rapid renewal of the different cell types
that constitute a multitasking tissue. The intestinal epithelium facilitates selective uptake of …

DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Neurodegenerative disorders are typically sporadic in nature in addition to usually
influenced through an extensive range of environmental factors, lifestyle, and genetic …

DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …

In recent years, cancer genomics has provided new insights into genetic alterations and
signaling pathways involved in thyroid cancer. However, the picture of the molecular …

Systemic targeted therapy in prostate cancer is primarily focused on ablating androgen
signaling. Androgen deprivation therapy and second-generation androgen receptor (AR) …

Ferroptosis, an iron-dependent form of selective cell death, is involved in the development of
many cancers. However, ferroptosis related genes (FRGs) in prostate cancer (PCa) are not …

DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …

It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …