Heterotopic Ossification (HO) is a lamellar bone formation in the soft tissues and usually
follows injury, trauma or joint replacement. A genome wide association study of HO patients …

Bladder cancer patients receive frequent screening due to the high tumor recurrence rate
(more than 60%). Nowadays, the conventional monitoring method relies on cystoscopy …

How a genotype gives rise to a phenotype is a century-old question. In the developmental
biology of cancer, decades of research have discovered various essential factors …

Despite this rising incidence of Human papillomavirus (HPV) driven head and neck cancer
(HNC) biomarkers for early detection and patient management are lacking. Considering the …

T-cell development and lineage commitment are temporally protracted processes in which
the interplay between transcription factors and epigenetic modulators orchestrate the …

A totipotent stem cell has the potential to give rise to the trillions of cells in the human body,
all carrying the very same genetic information. Through differentiation events, gene …

Increasing evidence indicates that insecticides induce various diseases via DNA
methylation. DNA methylation plays an important role during cell differentiation and exhibits …

In der vorliegenden Arbeit wurden mittels 5-Methylcytosin Immunofärbung zytogenetische
Analysen an Metaphasechromosomen aus der Mitose, an Interphase-Zellen verschiedener …

There is increasing interest in studying DNA methylation in the context of health and
disease. A number of technical and analytical considerations are important to take into …

Abstract ADNP encodes Activity-Dependent Neuroprotective Protein, whose de novo
heterozygous mutations cause Helsmoortel-Van der Aa Syndrome (HVDAS), a rare …