Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention

PR Angelova, N Esteras… - Medicinal Research …, 2021 - Wiley Online Library
The world's population aging progression renders age‐related neurodegenerative diseases
to be one of the biggest unsolved problems of modern society. Despite the progress in …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

[HTML][HTML] Flavonoids: Their putative neurologic roles, epigenetic changes, and gut microbiota alterations in Parkinson's disease

Y Açar, D Ağagündüz, P De Cicco… - Biomedicine & …, 2023 - Elsevier
Abstract Parkinson's Disease (PD), a neurodegenerative disorder, is characterized by the
degeneration of progressive dopaminergic (DA) neurons in the substantia nigra region of …

On the neuroprotective effects of naringenin: pharmacological targets, signaling pathways, molecular mechanisms, and clinical perspective

Z Nouri, S Fakhri, FF El-Senduny, N Sanadgol… - Biomolecules, 2019 - mdpi.com
As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …

Neuroprotective and symptomatic effects of cannabidiol in an animal model of Parkinson's disease

C Giuliano, M Francavilla, G Ongari, A Petese… - International Journal of …, 2021 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the Substantia Nigra pars compacta, leading to classical PD motor …

Multifunctional role of natural products for the treatment of Parkinson's disease: at a glance

MM Rahman, X Wang, MR Islam, S Akash… - Frontiers in …, 2022 - frontiersin.org
Natural substances originating from plants have long been used to treat neurodegenerative
disorders (NDs). Parkinson's disease (PD) is a ND. The deterioration and subsequent …

Naringenin: its chemistry and roles in neuroprotection

AV Atoki, PM Aja, TS Shinkafi, EN Ondari… - Nutritional …, 2024 - Taylor & Francis
According to epidemiological research, as the population ages, neurological illnesses are
becoming a bigger issue. Despite improvements in the treatment of these diseases, there …

Protective mechanism of Syringic acid in an experimental model of Parkinson's disease

Ö Güzelad, A Özkan, H Parlak, O Sinen, E Afşar… - Metabolic Brain …, 2021 - Springer
Hydroxydopamine (6-OHDA) is a widely used chemical to model Parkinson's disease (PD)
in rats. Syringic acid (SA) is a polyphenolic compound which has antioxidant and anti …

Inhibitory effects of Lentinus edodes mycelia polysaccharide on α-glucosidase, glycation activity and high glucose-induced cell damage

X Cao, Y Xia, D Liu, Y He, T Mu, Y Huo, J Liu - Carbohydrate polymers, 2020 - Elsevier
At present, diabetes and diabetic complications have become one of the serious diseases
affecting human health. In this study, the inhibitory effects of Lentinus edodes mycelia …

Hesperidin downregulates kinases lrrk2 and gsk3β in a 6-OHDA induced Parkinson's disease model

S Kesh, RR Kannan, K Sivaji, A Balakrishnan - Neuroscience letters, 2021 - Elsevier
The depletion of dopamine in the striatum region and Lewy bodies are the hallmark
characteristics of Parkinson's disease. The pathology also includes the upregulation of …