Mechanisms and strategies to enhance penetration during intravesical drug therapy for bladder cancer
P Zhang, G Wu, D Zhang, WF Lai - Journal of Controlled Release, 2023 - Elsevier
Bladder cancer (BCa) is one of the most prevalent cancers worldwide. The effectiveness of
intravesical therapy for bladder cancer, however, is limited due to the short dwell time and …
intravesical therapy for bladder cancer, however, is limited due to the short dwell time and …
The direct transfer approach for transcellular drug delivery
YF Wang, ZF Shen, F Xiang, H Wang, P Zhang… - Drug Delivery, 2023 - Taylor & Francis
A promising paradigm for drug administration that has garnered increasing attention in
recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT …
recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT …
[HTML][HTML] Influence of critical parameters on cytotoxicity induced by mesoporous silica nanoparticles
Mesoporous Silica Nanoparticles (MSNs) have received increasing attention in biomedical
applications due to their tuneable pore size, surface area, size, surface chemistry, and …
applications due to their tuneable pore size, surface area, size, surface chemistry, and …
Acid-sensing ion channel 1a activates IKCa/SKCa channels and contributes to endothelium-dependent dilation
Acid-sensing ion channel 1a (ASIC1a) belongs to a novel family of proton-gated cation
channels that are permeable to both Na+ and Ca2+. ASIC1a is expressed in vascular …
channels that are permeable to both Na+ and Ca2+. ASIC1a is expressed in vascular …
Impacts of arsenic on Rad18 and translesion synthesis
LB Volk, KL Cooper, T Jiang, ML Paffett… - Toxicology and applied …, 2022 - Elsevier
Arsenite interferes with DNA repair protein function resulting in the retention of UV-induced
DNA damage. Accumulated DNA damage promotes replication stress which is bypassed by …
DNA damage. Accumulated DNA damage promotes replication stress which is bypassed by …