Cardiac allograft vasculopathy: current review and future research directions

JS Pober, S Chih, J Kobashigawa… - Cardiovascular …, 2021 - academic.oup.com
Cardiac allograft vasculopathy (CAV) is a pathologic immune-mediated remodelling of the
vasculature in transplanted hearts and, by impairing perfusion, is the major cause of late …

Management of arrhythmias after heart transplant: current state and considerations for future research

JA Joglar, EY Wan, MK Chung, A Gutierrez… - Circulation …, 2021 - Am Heart Assoc
Orthotropic heart transplantation remains the most effective therapy for patients with end-
stage heart failure, with a median survival of≈ 13 years. Yet, a number of complications are …

The effect of lymphangiogenesis in transplant arteriosclerosis

K Chen, R Mou, P Zhu, X Xu, H Wang, L Jiang, Y Hu… - Circulation, 2023 - Am Heart Assoc
Background: Transplant arteriosclerosis is a major complication in long-term survivors of
heart transplantation. Increased lymph flow from donor heart to host lymph nodes has been …

Dyslipidemia in transplant patients: which therapy?

G Iannuzzo, G Cuomo, A Di Lorenzo… - Journal of Clinical …, 2022 - mdpi.com
Cardiovascular disease is the most important cause of death worldwide in recent years; an
increasing trend is also shown in organ transplant patients subjected to immunosuppressive …

Clonal hematopoiesis confers an increased mortality risk in orthotopic heart transplant recipients

FL Scolari, DH Brahmbhatt, S Abelson… - American journal of …, 2022 - Wiley Online Library
Novel risk stratification and non‐invasive surveillance methods are needed in orthotopic
heart transplant (OHT) to reduce morbidity and mortality post‐transplant. Clonal …

Molecular signature of antibody-mediated chronic vasculopathy in heart allografts in a novel mouse model

H Tsuda, N Dvorina, KS Keslar, J Nevarez-Mejia… - The American journal of …, 2022 - Elsevier
Cardiac allograft vasculopathy (CAV) limits the long-term success of heart transplants.
Generation of donor-specific antibodies (DSAs) is associated with increased incidence of …

Glucagon-like peptide 1 receptor agonists and cardiovascular outcomes in solid organ transplant recipients with diabetes mellitus

I Dotan, Y Rudman, A Turjeman, A Akirov… - …, 2024 - journals.lww.com
Background. Glucagon-like peptide 1 receptor agonists (GLP1-RAs) reduce cardiovascular
events and mortality in type 2 diabetes. Limited data are available on diabetes treatment …

Cholesterol lowering with EVOLocumab to prevent cardiac allograft Vasculopathy in De‐novo heart transplant recipients: Design of the randomized controlled …

K Broch, E Gude, K Karason, G Dellgren… - Clinical …, 2020 - Wiley Online Library
Background Cardiac allograft vasculopathy (CAV) is characterized by diffuse thickening of
the arterial intima. Statins reduce the incidence of CAV, but despite the use of statins, CAV …

High sensitivity troponin I as a biomarker for cardiac allograft vasculopathy: Evaluation of diagnostic potential and clinical utility

K Patel, A Yadalam, R DeStefano, S Desai… - Clinical …, 2024 - Wiley Online Library
Introduction Cardiac allograft vasculopathy (CAV) limits long‐term survival in heart
transplant (HTx) recipients. The use of biomarkers in CAV surveillance has been studied, but …

Invasive Intracoronary Imaging of Cardiac Allograft Vasculopathy: Established Modalities and Emerging Technologies.

N Shahandeh, RV Parikh - Interventional Cardiology Clinics, 2023 - europepmc.org
Despite advances in the care of heart transplant recipients during the past 5 decades,
cardiac allograft vasculopathy (CAV) continues to be a major barrier to long-term survival …