Magnetic resonance elastography from fundamental soft-tissue mechanics to diagnostic imaging
I Sack - Nature Reviews Physics, 2023 - nature.com
Magnetic resonance elastography (MRE) is a versatile imaging technique for mapping the
viscoelastic properties of soft biological tissues. It has been widely used to detect liver …
viscoelastic properties of soft biological tissues. It has been widely used to detect liver …
Mechanobiology of the brain in ageing and Alzheimer's disease
CM Hall, E Moeendarbary… - European Journal of …, 2021 - Wiley Online Library
Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …
influence its function, so too do its intrinsic mechanical properties and its extrinsic …
[HTML][HTML] Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties
G Bertalan, J Becker, H Tzschätzsch, A Morr… - Journal of the …, 2023 - Elsevier
Mechanical properties of brain tissue are very complex and vary with the species, region,
method, and dynamic range, and between in vivo and ex vivo measurements. To reconcile …
method, and dynamic range, and between in vivo and ex vivo measurements. To reconcile …
[HTML][HTML] Mechanical properties of murine hippocampal subregions investigated by atomic force microscopy and in vivo magnetic resonance elastography
AS Morr, M Nowicki, G Bertalan, R Vieira Silva… - Scientific Reports, 2022 - nature.com
The hippocampus is a very heterogeneous brain structure with different mechanical
properties reflecting its functional variety. In particular, adult neurogenesis in rodent …
properties reflecting its functional variety. In particular, adult neurogenesis in rodent …
[HTML][HTML] Contribution of tissue inflammation and blood-brain barrier disruption to brain softening in a mouse model of multiple sclerosis
RV Silva, AS Morr, S Mueller, SP Koch… - Frontiers in …, 2021 - frontiersin.org
Neuroinflammatory processes occurring during multiple sclerosis cause disseminated
softening of brain tissue, as quantified by in vivo magnetic resonance elastography (MRE) …
softening of brain tissue, as quantified by in vivo magnetic resonance elastography (MRE) …
[HTML][HTML] Cortical matrix remodeling as a hallmark of relapsing–remitting neuroinflammation in MR elastography and quantitative MRI
RV Silva, AS Morr, H Herthum, SP Koch, S Mueller… - Acta …, 2024 - Springer
Multiple sclerosis (MS) is a chronic neuroinflammatory disease that involves both white and
gray matter. Although gray matter damage is a major contributor to disability in MS patients …
gray matter. Although gray matter damage is a major contributor to disability in MS patients …
In vivo stiffness of multiple sclerosis lesions is similar to that of normal-appearing white matter
H Herthum, S Hetzer, M Scheel, M Shahryari, J Braun… - Acta Biomaterialia, 2022 - Elsevier
Abstract In 1868, French neurologist Jean-Martin Charcot coined the term multiple sclerosis
(MS) after his observation that numerous white matter (WM) glial scars felt like sclerotic …
(MS) after his observation that numerous white matter (WM) glial scars felt like sclerotic …
[HTML][HTML] Real-time multifrequency MR elastography of the human brain reveals rapid changes in viscoelasticity in response to the Valsalva maneuver
H Herthum, M Shahryari, H Tzschätzsch… - … in Bioengineering and …, 2021 - frontiersin.org
Modulation of cerebral blood flow and vascular compliance plays an important role in the
regulation of intracranial pressure (ICP) and also influences the viscoelastic properties of …
regulation of intracranial pressure (ICP) and also influences the viscoelastic properties of …
Superviscous properties of the in vivo brain at large scales
There is growing awareness that brain mechanical properties are important for neural
development and health. However, published values of brain stiffness differ by orders of …
development and health. However, published values of brain stiffness differ by orders of …
Microscale characterisation of the time-dependent mechanical behaviour of brain white matter
A Jamal, A Bernardini, D Dini - Journal of the Mechanical Behavior of …, 2022 - Elsevier
Brain mechanics is a topic of deep interest because of the significant role of mechanical
cues in both brain function and form. Specifically, capturing the heterogeneous and …
cues in both brain function and form. Specifically, capturing the heterogeneous and …