Drug-induced liver disease

JH Lewis - Medical Clinics, 2000 - medical.theclinics.com
Of the numerous medicinal agents, chemicals, and herbal remedies in existence, more than
600 are recognized as producing hepatic injury. 2o5 The incidence of drug-induced liver …

Hepatotoxicity during rapid intravenous loading with amiodarone: description of three cases and review of the literature

AER Bravo, J Drewe, RG Schlienger… - Critical care …, 2005 - journals.lww.com
Objective: Atrial fibrillation is the most common arrhythmia after cardiac surgery. Amiodarone
can effectively prevent and control postoperative atrial and ventricular fibrillation. Acute …

Acute liver failure with amiodarone infusion: A case report and systematic review

P Jaiswal, BM Attar, JE Yap, K Devani… - Journal of clinical …, 2018 - Wiley Online Library
What is known and objective Amiodarone, a commonly used class III antiarrhythmic agent
notable for a relatively long half‐life of up to 6 months and its pronounced adverse effect …

Hyperacute drug-induced hepatitis with intravenous amiodarone: case report and review of the literature

M Nasser, TR Larsen, B Waanbah, I Sidiqi… - Drug, healthcare and …, 2013 - Taylor & Francis
Amiodarone is a benzofuran class III antiarrhythmic drug used to treat a wide spectrum of
ventricular tachyarrhythmias. The parenteral formulation is prepared in polysorbate 80 …

Amiodarone‐Induced Cirrhosis of Liver: What Predicts Mortality?

N Hussain, A Bhattacharyya… - International Scholarly …, 2013 - Wiley Online Library
Introduction. Amiodarone has been used for more than 5 decades for the treatment of
various tachyarrhythmias and previously for the treatment of refractory angina. There are …

Retrospective evaluation of the use of amiodarone in dogs with arrhythmias (from 2003 to 2010)

B Pedro, J López‐Alvarez, S Fonfara… - Journal of Small …, 2012 - Wiley Online Library
Objectives: To evaluate the efficacy of amiodarone in dogs with refractory supraventricular
and ventricular arrhythmias and to document the side effects in treated dogs. Methods …

Use of population modeling to define rational monitoring of amiodarone hepatic effects

PT Pollak, SL Shafer - Clinical Pharmacology & Therapeutics, 2004 - Wiley Online Library
Background Amiodarone causes hepatotoxicity in experimental models, but in humans, the
relationships between drug administration, serum concentrations, markers of liver function …

Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs

S Endo, Y Toyoda, T Fukami, M Nakajima… - Drug metabolism and …, 2012 - Elsevier
Drug-induced liver injury (DILI) is thought to be involved in the participation of drugs that
either directly affect the cell viability or elicit an immune response. However, there is limited …

Hepatotoxicity of cardiovascular and antidiabetic drugs

D Halegoua-De Marzio, VJ Navarro - Drug-induced liver disease, 2013 - Elsevier
With the increasing prevalence of cardiovascular disease and associated disorders globally,
there has been a proliferation of medications for antiplatelet therapy, dyslipidemia, glycemic …

[HTML][HTML] Acute hepatitis after amiodarone infusion

P Fonseca, A Dias, H Gonçalves… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Acute hepatitis is a very rare, but potentially fatal, adverse effect of intravenous amiodarone.
We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy …